Modular Sampling System Initiative Background and Status 2000 Spring Sponsor Meeting Center for Process Analytical Chemistry

Background and Chronology of Activities O&P Focus Group May 1999 Identified Sampling Systems as Area Of Interest Sponsored Tutorial for Nov99 Sponsor Meeting Tutorial Nov99 CPAC Meeting Background/Reasons for Interest Presentations by Suppliers/ End Users Participation in IFPAC2000Meeting Ad-hoc O&P Meeting @ Pittcon2000 Follow-up Meeting CPAC2000 What is Next?

O&P Focus Group Meeting May 99 Recognized Modular Sampling System Efforts in Semi Conductor Industry (Standard) Vendors like Autoflow, A+, Swagelok etc. promoted modular designs Recognized that current implementations of sample systems designs have not changed for many years CPAC has promoted Versatile Micro Analytical Systems (VMAS) as a basis for future micro-analytical techniques O&P decided to sponsor a SSISSS (Small Smart Integrated Sensor and Sampling System) Tutorial at CPAC Nov Meeting

Nov99 CPAC SSISSS Tutorial ExxonMobil/DuPont Provided Introduction to Tutorial Validation of Sample System Performance Integration of Sensor with Sampling System Four Suppliers of Sampling/Analyzer Systems Participated in Tutorial: A+, Autoflow, Swagelok, Rosemount Many components commercially Available GCX example of self-contained miniaturized GC (GC on a pole) Recognition Modular Sampling System can be a platform to integrate VMAS Bridge between Process Sample (Macro world) Micro Fluidics Sensors/Analyzers

Driving Forces for Change Reduce Cost of Ownership Non Recurring Costs = Cost to Build Operating Cost Data Validation (Fit for Use)

A P T F Integration of Sample System and Sensors Mainly a Trust Configuration Now a Trust & Verify Configuration A Analyzer Controller Field LAN Sample Conditioning System F T P Process Stream All System Components in Contact with Sample including the Sensors All Additional Electronic and Computing Components Required to Generate Analytical Result Level 0 Level 1

A P T F Level 0 Subsystem Integration Purpose: Prepare and Verify a Representative Sample (Compatible with Analyzer Sensor) Integrated Sampling/Sensor System A Sample Conditioning System F T P Opportunity: Packaging as an Integrated Sensor and Sampling System Size Cost Process Stream Issues: Size Standardization VMAS Level 0

A P T F Separation or Integration of Level 0/1 Subsystems Objective: Analyzer Controller Field LAN F T P Objective: Close to Sample Tap Process Stream Integrated Sampling/Sensor System Options: Remote Separate but Close Integrated Level 0 Level 1

$$ A P T F Integration of Level 0/1 Subsystems Integrated Sampling/Sensor/Controller System A Analyzer Controller Field LAN F T P Process Stream $$ Level 0 Level 1

Nov99 CPAC SSISSS Tutorial ExxonMobil/DuPont Provided Introduction to Tutorial Validation of Sample System Performance Integration of Sensor with Sampling System Four Suppliers of Sampling/Analyzer Systems Participated in Tutorial: A+, Autoflow, Swagelok, Rosemount Many components commercially Available GCX example of self-contained miniaturized GC (GC on a pole) Recognition Modular Sampling System can be a platform to integrate VMAS Bridge between Process Sample (Macro world) Micro Fluidics Sensors/Analyzers

Nov99 CPAC SSISSS Tutorial (Vendor Presentations) Swagelok Autoflow A+ Rosemount

Nov99 CPAC SSISSS Tutorial ExxonMobil/DuPont Provided Introduction to Tutorial Validation of Sample System Performance Integration of Sensor with Sampling System Four Suppliers of Sampling/Analyzer Systems Participated in Tutorial: A+, Autoflow, Swagelok, Rosemount Many components commercially Available GCX example of self-contained miniaturized GC (GC on a pole) Recognition Modular Sampling System can be a platform to integrate VMAS Bridge between Process Sample (Macro world) and Micro Fluidics Sensors/Analyzers

IFPAC2000 ExxonMobil Presented Plenary Paper Promoting SSISSS Sample System Infrastructure accounts for 50+% Cost to Build Proposed Conceptual Design for SSISSS Highlighted sensor and analyzer transmitter configurations Sampling System Session Presentations by A+, Autoflow, etc. Sampling Systems enjoyed a High Profile CPAC/ExxonMobil sponsored Workshop Confirmed high interest in Modular Sampling System Provided input for the ISA Standardization effort

For a major greenfield project TODAY’S COST OF BUILD For a major greenfield project

TODAY’S COST OF OWNERSHIP

IMAGINE THE FUTURE A P T F Field LAN Process Stream Level 0 Level 1 Analyzer Controller T F Level 0 Level 1

IMAGINE THE FUTURE P F T A Sensor = Moisture Probe Sensor/Signal Bus FLAN (Optical Fiber) P F IA Controller(ASIC) & Interface Module T A Sensor/Signal Bus Original Picture of Gas Delivery System courtesy Valin Corporation;

IMAGINE THE FUTURE Sensor = RAMAN Probe P F T Interface Module A

Sensor = Moisture Probe IMAGINE THE FUTURE FLAN (Optical Fiber) Sensor/Signal Bus IA Controller (ASIC) A T P F Sensor = Moisture Probe

IMAGINE THE FUTURE GCX Picture courtesy Rosemount Analytical

IFPAC2000 ExxonMobil Presented Plenary Paper Promoting SSISSS Sample System Infrastructure accounts for 50+% Cost to Build Proposed Conceptual Design fro SSISSS Highlighted sensor and analyzer transmitter configurations Sampling System Session Presentations by A+, Autoflow, etc. Sampling Systems enjoyed a High Profile CPAC/ExxonMobil sponsored Workshop Confirmed high interest in Modular Sampling System Provided input for the ISA Standardization effort

IFPAC2000 ExxonMobil Presented Plenary Paper Promoting SSISSS Sample System Infrastructure accounts for 50+% Cost to Build Proposed Conceptual Design fro SSISSS Highlighted sensor and analyzer transmitter configurations Sampling System Session Presentations by A+, Autoflow, etc. Sampling Systems enjoyed a High Profile CPAC/ExxonMobil sponsored Workshop Confirmed high interest in Modular Sampling System Provided input for the ISA Standardization effort

Pittcon2000 (New Orleans) O&P Ad-Hoc Meeting of Sponsor End-users DuPont, Dow, Dow-Corning, CPAC, Rohm&Haas, ExxonMobil Main Goal: Identify Typical Sample System Designs as Candidates for Modular Design Reviewed some typical gas/liquid sample System Designs Rob DuBois Presented a Modular Component/Service Matrix Discussed next steps Present Sample System Data at May CPAC Meeting Next Step is to Open Up Discussion (3rd parties) Leverage ISA Meeting in New Orleans (Aug00) Role of CPAC in Facilitating Development/Testing of a Prototype System Larry Ricker/Lloyd Burgess to Present Proposal

Status CPAC Meeting May 1999 Done O&P Identified Modular Sampling Systems CPAC Meeting Nov 1999 Done O&P Sponsored Tutorial IFPAC2000 Meeting Done Plenary Presentation Promoted SSISS Session on Modular Sampling Systems CPAC Sponsored Workshop Pittcon2000 Done Ad-hoc O&P Meeting Propose Candidate Sampling System Descriptions CPAC Meeting May 2000 TBD

What is Next? CPAC Meeting May 2000 (Sampling Focus Group – Wednesday) Review and Agree on Sample System Information Package Involvement of 3rd parties How do we distribute package (Distribution List, Meeting?) Expectations for proposals from Suppliers (Paper designs?) Joint Effort with ISA (Meeting in Aug, New Orleans) Evaluation of Designs - Recommendation Prototype design/manufacturing/testing at CPAC Larry Ricker/Lloyd Burgess proposal Program to Evaluate Test Platforms fro Micro Analytical Devices CPAC Proposal – Lloyd Burgess

Acknowledgements Dow – Rob Dubois/Ron O’Reily/Brian Worthington Dow Corning - Jim Tatera/Gary Bokerman DuPont - Bob Bucher Rohm&Haas – Joe Sung Honeywell - Ken Creasy Akzo Nobel – Foad Mozayeni CPAC - Lloyd Burgess/Larry Ricker