Epidemiology and a novel procedure for large scale analysis of CFTR rearrangements in classic and atypical CF patients: A multicentric Italian study

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Presentation transcript:

Epidemiology and a novel procedure for large scale analysis of CFTR rearrangements in classic and atypical CF patients: A multicentric Italian study R. Tomaiuolo, F. Sangiuolo, C. Bombieri, A. Bonizzato, G. Cardillo, V. Raia, M.R. D'Apice, M.D. Bettin, P.F. Pignatti, G. Castaldo, G. Novelli Journal of Cystic Fibrosis Volume 7, Issue 5, Pages 347-351 (September 2008) DOI: 10.1016/j.jcf.2007.12.004 Copyright © 2007 European Cystic Fibrosis Society Terms and Conditions

Fig. 1 Duplex PCR assay of the seven rearrangements. A) Gel electrophoresis and B) schematic representation of the pattern in seven different heterozygous patients bearing: 1) dele_1; 2) dele_2; 3) dele2_3; 4) dele14b_17b; 5) dele17a_18; 6) dele22_23; 7) dele22_24 and s.m) 100 bp size marker. Journal of Cystic Fibrosis 2008 7, 347-351DOI: (10.1016/j.jcf.2007.12.004) Copyright © 2007 European Cystic Fibrosis Society Terms and Conditions