Ivan C. Gerling et al. JCHF 2013;1:469-476 Heat Map of Gene Expression Profiles in Heart Tissue From Control and Aldosterone-Salt Treated Rats (A) Heat map of gene expression for control, week 1 and 4 aldosterone/salt treatment (ALDOST). Results from hierarchical clustering of the 83 probe sets in heart tissue affected by ALDOST. Red indicates relatively high expression, whereas blue indicates relatively low expression. Each group had 6 rats. (B) Network created by the Ingenuity server from the genes in heart tissue shown in A. The gray nodes indicate genes that are significantly affected by ALDOST, whereas the white icons represent genes, gene families, and molecules that are needed to connect those ALDOST-affected genes to each other in a network. Ivan C. Gerling et al. JCHF 2013;1:469-476 American College of Cardiology Foundation