Pulmonary Cytolytic Thrombi after Allogeneic Hematopoietic Cell Transplantation: A Further Histologic Description  Antoinette Peters, J. Carlos Manivel, Michelle Dolan, H. Evin Gulbahce, K. Scott Baker, Michael R. Verneris  Biology of Blood and Marrow Transplantation  Volume 11, Issue 6, Pages 484-485 (June 2005) DOI: 10.1016/j.bbmt.2005.03.009 Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Histologic evaluation of cytolytic thrombi. A, Pulmonary cytolytic thrombus. The thrombus consists predominantly of cells with monocytoid features; the muscular wall of the artery can be seen on top (stain, hematoxylin and eosin; original magnification, ×600). B, Strong membrane reactivity for common leukocyte antigen. A negatively stained arterial wall is seen at the right (immunoperoxidase stain for CD45; original magnification, ×600). C, Intense cytoplasmic reactivity for the monocyte-macrophage marker CD68. A negatively stained arterial wall is seen at the bottom right (immunoperoxidase stain; original magnification, ×600). D, Intense cytoplasmic reactivity for myeloperoxidase is seen in cells of the cytolytic thrombus. A negatively stained arterial wall is seen at the left (immunoperoxidase stain; original magnification, ×600). E, Fluorescence in situ hybridization analysis showing 2 cells of female origin (2 green centromere X signals) and 1 male cell (1 green centromere X signal and 1 red centromere Y signal). Biology of Blood and Marrow Transplantation 2005 11, 484-485DOI: (10.1016/j.bbmt.2005.03.009) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions