Expression Of Human Chorionic Gonadotropin β-Subunit Type I Genes Predicts Adverse Outcome In Renal Cell Carcinoma Kristina Hotakainen, Susanna Lintula,

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Expression Of Human Chorionic Gonadotropin β-Subunit Type I Genes Predicts Adverse Outcome In Renal Cell Carcinoma Kristina Hotakainen, Susanna Lintula, Börje Ljungberg, Patrik Finne, Annukka Paju, Ulf-Håkan Stenman, Jakob Stenman The Journal of Molecular Diagnostics Volume 8, Issue 5, Pages 598-603 (November 2006) DOI: 10.2353/jmoldx.2006.060076 Copyright © 2006 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 Standard curve of the quantitative RT-PCR assay for hCGβ mRNA. WT, wild-type hCGβ. Whiskers represent standard errors. The Journal of Molecular Diagnostics 2006 8, 598-603DOI: (10.2353/jmoldx.2006.060076) Copyright © 2006 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 2 Disease-specific survival of RCC patients with type I hCGβ mRNA-positive tumors (n = 42) compared with those with hCGβ mRNA-negative tumors (n = 62; log-rank P = 0.0234; Breslow P = 0.0029 (A), disease-specific survival in CRCCs (n = 79; log-rank P = 0.15 and Breslow P = 0.026) (B), and papillary chromophobe as well as unclassified tumors (n = 25; log-rank P = 0.017; Breslow P = 0.019) (C). The Journal of Molecular Diagnostics 2006 8, 598-603DOI: (10.2353/jmoldx.2006.060076) Copyright © 2006 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions