Health-related quality of life predicts outcomes but is not affected by peritoneal clearance: The ADEMEX trial Ramon Paniagua, Dante Amato, Edward Vonesh,

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Health-related quality of life predicts outcomes but is not affected by peritoneal clearance: The ADEMEX trial Ramon Paniagua, Dante Amato, Edward Vonesh, Amy Guo, Salim Mujais Kidney International Volume 67, Issue 3, Pages 1093-1104 (March 2005) DOI: 10.1111/j.1523-1755.2005.00175.x Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 1 Physical component summary scores (PCS) (mean ± 1 SE) by pattern of patient dropout (or last measured QOL). Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 2 Mental component summary scores (MCS) (mean ± 1 SE) by pattern of patient dropout (or last measured QOL). Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 3 Kidney disease component summary scores (KDCS) (mean ± 1 SE) by pattern of patient dropout (or last measured QOL). Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 4 Comparison of adjusted physical component summary scores (PCS) temporal profiles in the control and intervention groups. No differences between the two groups were observed at any time point. Mean ± 1 SE. Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 5 Comparison of adjusted mental component summary scores (MCS) temporal profiles in the control and intervention groups. No differences between the two groups were observed at any time point. Mean ± 1 SE. Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 6 Comparison of adjusted kidney disease component summary scores (KDCS) temporal profiles in the control and intervention groups. No differences between the two groups were observed at any time point. Mean ± 1 SE. Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 7 Adjusted versus unadjusted physical component summary scores over time in the two groups. Use of unadjusted values would have obscured the temporal decline in HRQOL in both groups. Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 8 (A) Patient survival by value of physical composite summary score (PCS) and study arm. Patients with PCS values below the mean (<37.5) had a worse survival than patients above the mean irrespective of the study arm they were randomized to. There were no differences between control and intervention in either subset of PCS. (B) Patient survival by value of mental composite summary score (MCS) and study arm. Patients with MCS values below the mean (<50) had a worse survival than patients above the mean irrespective of the study arm they were randomized to. There were no differences between control and intervention in either subset of MCS. (C) Patient survival by value of kidney disease composite summary score (KDCS) and study arm. Patients with KDCS values below the mean (<53) had a worse survival than patients above the mean irrespective of the study arm they were randomized to. There were no differences between control and intervention in either subset of KDCS. Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 9 (A) Composite summary scores in patients on peritoneal dialysis (PD) (ADEMEX) and patients on hemodialysis (DOPPS), the latter data from ref23. (B) SF-36 domain scores in patients on PD (ADEMEX) and patients on hemodialysis (DOPPS), the latter data from ref23. (C) Disease-specific domain scores in patients on PD (ADEMEX) and patients on hemodialysis (DOPPS), the latter data from ref23. Kidney International 2005 67, 1093-1104DOI: (10.1111/j.1523-1755.2005.00175.x) Copyright © 2005 International Society of Nephrology Terms and Conditions