Neighbourhood socioeconomic disadvantage, risk factors, and diabetes from childhood to middle age in the Young Finns Study: a cohort study  Prof Mika.

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Neighbourhood socioeconomic disadvantage, risk factors, and diabetes from childhood to middle age in the Young Finns Study: a cohort study  Prof Mika Kivimäki, FMedSci, Prof Jussi Vahtera, MD, Adam G Tabák, MD, Jaana I Halonen, PhD, Prof Paolo Vineis, MD, Jaana Pentti, MSc, Katja Pahkala, PhD, Suvi Rovio, PhD, Prof Jorma Viikari, MD, Prof Mika Kähönen, MD, Prof Markus Juonala, MD, Jane E Ferrie, PhD, Silvia Stringhini, PhD, Prof Olli T Raitakari, MD  The Lancet Public Health  Volume 3, Issue 8, Pages e365-e373 (August 2018) DOI: 10.1016/S2468-2667(18)30111-7 Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 1 Study profile The Lancet Public Health 2018 3, e365-e373DOI: (10.1016/S2468-2667(18)30111-7) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 2 Risk factors of cardiometabolic health by age and cumulative neighbourhood socioeconomic disadvantage The cutoff for high neighbourhood socioeconomic disadvantage is >0·5 SD above the national mean and the cutoff for low neighbourhood socioeconomic disadvantage is more than or equal to 0·5 SD below the national mean. Data for those with intermediate low and high neighbourhood socioeconomic disadvantage are given in the appendix. The Lancet Public Health 2018 3, e365-e373DOI: (10.1016/S2468-2667(18)30111-7) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 3 Risk factors for diabetes by age and cumulative neighbourhood socioeconomic disadvantage The cutoff for high neighbourhood socioeconomic disadvantage is >0·5 SD above the national mean and the cutoff for low neighbourhood socioeconomic disadvantage is more than or equal to 0·5 SD below the national mean. Data for those with intermediate low and high neighbourhood socioeconomic disadvantage are given in the appendix. HOMA-S=homoeostasis model assessment insulin sensitivity. The Lancet Public Health 2018 3, e365-e373DOI: (10.1016/S2468-2667(18)30111-7) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions

Figure 4 Association of cumulative neighbourhood socioeconomic disadvantage with incident diabetes in adulthood In Models 1 and 2, SD refers to national mean. In Model 3, the cutoff for high versus low neighbourhood socioeconomic disadvantage is the national mean score of 0. Disadvantage trajectory refers to neighbourhood socioeconomic disadvantage from childhood to adulthood. n=number of diabetes cases. N=total participants. The Lancet Public Health 2018 3, e365-e373DOI: (10.1016/S2468-2667(18)30111-7) Copyright © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Terms and Conditions