Legends in allergy: Philip S. Norman and Lawrence M

Slides:

Advertisements

Similar presentations

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Advertisements

D-dimer: A biomarker for antihistamine-resistant chronic urticaria

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

What drives prescription patterns in pediatric asthma management?

Susan L. Limb, MD, Kathryn C. Brown, MD, Robert A. Wood, MD, Robert A

Effect of 2-year placebo-controlled immunotherapy on airway symptoms and medication in patients with birch pollen allergy Monica B. Arvidsson, MD, Olle.

Allergen immunotherapy: A practice parameter third update

Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses Stephen R. Durham,

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

High-titer IgE antibody specific for pollen allergens in northern California is associated with both wheezing and total serum IgE Elizabeth A. Erwin,

Treatment effect of sublingual immunotherapy tablets and pharmacotherapies for seasonal and perennial allergic rhinitis: Pooled analyses Stephen R. Durham,

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Fluticasone furoate nasal spray: A single treatment option for the symptoms of seasonal allergic rhinitis Harold B. Kaiser, MD, Robert M. Naclerio, MD,

Randomized controlled trial of a ragweed allergy immunotherapy tablet in North American and European adults Peter S. Creticos, MD, Jennifer Maloney,

Epicutaneous allergen administration as a novel method of allergen-specific immunotherapy Gabriela Senti, MD, Nicole Graf, PhD, Susanne Haug, MD, Nadine.

Epicutaneous allergen-specific immunotherapy ameliorates grass pollen–induced rhinoconjunctivitis: A double-blind, placebo-controlled dose escalation.

Disparities in allergic disease: Hypersensitivity and social disorders

Is 9 more than 2 also in allergic airway inflammation?

Bruce M. Prenner, MD, Bobby Q. Lanier, MD, David I

Jack Pepys' contributions to the medical literature

Characterization of pollen antigen–induced IL-31 production by PBMCs in patients with allergic rhinitis Mitsuhiro Okano, MD, Tazuko Fujiwara, BS, Takaya.

Practice Notes from the AAAAI

A history of pollen mapping and surveillance: The relations between natural history and clinical allergy Gregg Mitman, PhD Journal of Allergy and Clinical.

Stanley J. Szefler, MD, Richard J. Martin, MD

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Peter M. Wolfgram, MD, David B. Allen, MD

Asthma symptom re-emergence after omalizumab withdrawal correlates well with increasing IgE and decreasing pharmacokinetic concentrations Raymond G.

Successful management of mite-allergic asthma with modified extracts of Dermatophagoides pteronyssinus and Dermatophagoides farinae in a double-blind,

Reply Journal of Allergy and Clinical Immunology

Phillip Lieberman, MD, Michael Tankersley, MD

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

Cluster analysis and prediction of treatment outcomes for chronic rhinosinusitis Zachary M. Soler, MD, MSc, J. Madison Hyer, MS, Luke Rudmik, MD, MSc,

Chronic rhinosinusitis: Endotypes, biomarkers, and treatment response

Phillip Lieberman, MD, David Golden, MD

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Allergen-specific immunotherapy with recombinant grass pollen allergens Marek Jutel, MD, Lothar Jaeger, MD, Roland Suck, PhD, Hanns Meyer, Dipl Math,

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Claus Bachert, MD, PhD, Cezmi A. Akdis, MD

Insect sting allergy and venom immunotherapy: A model and a mystery

What is an “eosinophilic phenotype” of asthma?

Cephalosporin Side Chain Cross-reactivity

Medication use in children with asthma in Finland from 1995 to 2006

Treating acute rhinosinusitis: Comparing efficacy and safety of mometasone furoate nasal spray, amoxicillin, and placebo Eli O. Meltzer, MD, Claus Bachert,

What the asthma end points we know and love do and do not tell us

H. William Kelly, PharmD Journal of Allergy and Clinical Immunology

Autophagy: Nobel Prize 2016 and allergy and asthma research

Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis Thomas B. Casale, MD, William.

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

Advances in the approach to the patient with food allergy

Piotr Kuna, MD, Jadwiga Kaczmarek, MD, Maciej Kupczyk, MD

Benjamin Chaigne, MD, Hervé Watier, MD, PhD

The National Institutes of Allergy and Infectious Diseases networks on asthma in inner- city children: An approach to improved care William W. Busse,

Martin Brasholt, MD, Florent Baty, PhD, Hans Bisgaard, MD, DMSci

Association between climate factors, pollen counts, and childhood hay fever prevalence in the United States Jonathan I. Silverberg, MD, PhD, MPH, Marc.

Thunderstorm-related asthma attacks

An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment Eli O. Meltzer, MD, Robert B. Berkowitz,

Advances in basic and clinical immunology in 2013

Measles and immunomodulation

Macrolide antibiotics and asthma treatment

Asthma: The past, future, environment, and costs

Fiftieth Annual Meeting of the American Academy of Allergy and Immunology: Anaheim, California, March 1994 Lawrence M. Lichtenstein, MD, PhD Journal.

The correlation between allergic rhinitis and sleep disturbance

Efficacy of a short course of specific immunotherapy in patients with allergic rhinoconjunctivitis to ragweed pollen Piyush Patel, MD, Tom Holdich, MBBS,

The GILL study: Glycerin-induced local reactions in immunotherapy

Lisa A. Beck, MD, Sarbjit Saini, MD

Double-blind, placebo-controlled study with a modified therapeutic vaccine of Salsola kali (Russian thistle) administered through use of a cluster schedule

An intranasal Syk-kinase inhibitor (R112) improves the symptoms of seasonal allergic rhinitis in a park environment Eli O. Meltzer, MD, Robert B. Berkowitz,

Natural history of cow’s milk allergy

Susan L. Janson, DNSc, Kelly Wong McGrath, BA, Jack K

Primary prevention of asthma and allergy

Presentation transcript:

Legends in allergy: Philip S. Norman and Lawrence M Legends in allergy: Philip S. Norman and Lawrence M. Lichtenstein—The Hopkins Experience Peter Socrates Creticos, MD Journal of Allergy and Clinical Immunology Volume 119, Issue 4, Pages 1031-1038 (April 2007) DOI: 10.1016/j.jaci.2007.02.035 Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Average daily symptom scores of groups of patients with hay fever treated with antigen E, whole ragweed extract, or placebo in 1966. Reprinted with permission from Norman PS, Winkenwerder WL, Lichtenstein LM. Immunotherapy of hay fever with ragweed antigen E: comparisons with whole pollen extract and placebos. J Allergy 1968;42:93-108.18 Journal of Allergy and Clinical Immunology 2007 119, 1031-1038DOI: (10.1016/j.jaci.2007.02.035) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Arithmetic mean of daily symptom-medication scores for the groups indicated compared with the pollen count reported as ragweed pollen grains per cm2 of rotoslide. Rise and fall of symptom medication scores were significantly correlated with rise and fall of ragweed pollen counts for standard ragweed group (Spearman correlation coefficient, rs = .696, P < .01), placebo group (rs = .626, P ≤ .01), Rinkel 78/79 group (rs = .718, P < .01), and Rinkel 79 group (rs = .603, P < .01). Symptom medication scores of standard group were significantly less (P < .01) than those of Rinkel and placebo groups; those of Rinkel and placebo groups were not significantly different (P = .30). Reprinted with permission from Van Metre TE, Adkinson NF, Amodio FJ, Lichtenstein LM, Mardiney MR, Norman PS, et al. A comparative study of the effectiveness of the Rinkel method and the current standard method of immunotherapy for ragweed pollen hay fever. J Allergy Clin Immunol 1980;66:500-13. Journal of Allergy and Clinical Immunology 2007 119, 1031-1038DOI: (10.1016/j.jaci.2007.02.035) Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions