Ribosome Evolution for Two Artificial Amino Acids in E. coli

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Ribosome Evolution for Two Artificial Amino Acids in E. coli Gosuke Hayashi, Yuki Goto, Hiroaki Suga Chemistry & Biology Volume 17, Issue 4, Pages 320-321 (April 2010) DOI: 10.1016/j.chembiol.2010.04.005 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Decoding an mRNA Four-Base Codon in a Ribosome (A) Orthogonal relationship between wild-type ribosome-mRNA and orthogonal ribosome-mRNA. (B) Decoding four-base codon in the A site. (C) Decoding four-base codon in the P site. There are multiple possibilities of the decoding mode depending upon the sequences of four-base codon and neighboring codons. Numbers colored in red or black represent numbering of anticodon or mRNA bases, respectively. An expanded base on a quadruplet anticodon is indicated as 33.5 in dark red. Chemistry & Biology 2010 17, 320-321DOI: (10.1016/j.chembiol.2010.04.005) Copyright © 2010 Elsevier Ltd Terms and Conditions