Hemodynamic stress and experimental aortoiliac atherosclerosis

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Presentation transcript:

Hemodynamic stress and experimental aortoiliac atherosclerosis Hisham S. Bassiouny, MD, Christopher K. Zarins, MD, Mark H. Kadowaki, MD, Seymour Glagov, MD Journal of Vascular Surgery Volume 19, Issue 3, Pages 426-434 (March 1994) DOI: 10.1016/S0741-5214(94)70069-9 Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 1 Typical atherosclerotic lesion in abdominal and thoracic aorta. Lesion consisted of predominantly foam cells above internal elastic lamina (I) and media. Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 2 Mean heart rate frequency distribution. Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 3 Mean systemic blood pressure frequency distribution (in millimeters of mercury). Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 4 Pulsed Doppler spectral analysis if infrarenal aorta shows characteristic triphasic profile with flow reversal in late systole. Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 5 Pulsed-wave Doppler spectral analysis of supraceliac aorta. Flow profile is biphasic, with no flow reversal at end systole and notable diastolic flow. Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 6 Hemodynamic stress index frequency distribution. Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Fig. 7 Linear regression analysis of hemodynamic stress index versus maximum lesion thickness in aortoiliac segment. Journal of Vascular Surgery 1994 19, 426-434DOI: (10.1016/S0741-5214(94)70069-9) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions