Epithelial Contractility: A Crowning Achievement

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Epithelial Contractility: A Crowning Achievement Jeanne N. Jodoin, Adam C. Martin Developmental Cell Volume 37, Issue 1, Pages 3-4 (April 2016) DOI: 10.1016/j.devcel.2016.03.017 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure 1 Junctional Actomyosin Reorganization Required for Contractility (A) A mature actomyosin network is present at cell-cell contacts. (B) Following F-actin depolymerization, junctional actomyosin network is organized via two steps: actomyosin nucleation and actomyosin alignment. (C) Apoptosis (purple cell) produces a mechanical stimulus that recruits Coro1B to junctions through E-cadherin to upregulate and align junctional actomyosin and drive apoptotic cell extrusion. Developmental Cell 2016 37, 3-4DOI: (10.1016/j.devcel.2016.03.017) Copyright © 2016 Elsevier Inc. Terms and Conditions