Local activation delay exacerbates local J-ST elevation in the epicardium: Electrophysiological substrate in Brugada syndrome  Naoya Kataoka, MD, PhD,

Slides:



Advertisements
Similar presentations
Abnormal epicardial electrophysiologic substrate in patients with early repolarization pattern and reduced left ventricular systolic function: A report.
Advertisements

Radiofrequency ablation of premature ventricular contractions originating from the aortomitral continuity localized by use of a novel noninvasive epicardial.
Wolff-Parkinson-White syndrome due to a left atrial appendage–to–left ventricular connection: A case of a successful pathway elimination from inside of.
Successful ablation of ventricular tachycardia arising from a midmyocardial septal outflow tract site utilizing a simplified bipolar ablation setup  Peter.
Successful ablation of premature ventricular contractions originating from the inferoseptal process of the left ventricle using a coronary sinus approach 
Appearance of J wave in the inferolateral leads and ventricular fibrillation provoked by mild hypothermia in a patient with Brugada syndrome  Yasuaki.
Ablation of ventricular tachycardia from the aortic root after transcatheter aortic valve replacement  Uma N. Srivatsa, MBBS, MAS, FHRS, Eric J. Nordsieck,
Reduced desmoplakin immunofluorescence signal in arrhythmogenic cardiomyopathy with epicardial right ventricular outflow tract tachycardia  Sabina Rosset,
Premature ventricular contractions with two QRS morphologies originate from one focus in great cardiac vein  Juan Ma, MD, Ke-Xiang Wu, MD, Yu-Bin Wang,
Correlation between functional and ultrastructural substrate in Brugada syndrome  Pablo E. Tauber, MD, Virginia Mansilla, MD, Guillermo Mercau, MD, Felix.
First case of epicardial ablation to coexistent J waves in the inferior leads in a patient with clinical diagnosis of Brugada syndrome  Shingo Maeda,
Successful elimination of recurrent ventricular tachycardia by epicardial ablation over coronary artery supplying postinfarction aneurysm  Kenichiro Yamagata,
Epicardial substrate ablation for Brugada syndrome
Is it bradycardia or something else causing symptoms?
T-wave oversensing during drug challenge test after subcutaneous implantable cardioverter-defibrillator implantation in a patient with Brugada syndrome 
Concomitant Brugada syndrome substrate ablation and epicardial abdominal cardioverter-defibrillator implantation in a child  Carlo de Asmundis, MD, PhD,
HeartRhythm Case Reports
Volume 13, Issue 1, Pages (January 2016)
Ablation of epicardial ventricular tachycardia in a chagasic patient with situs inversus totalis: A case report  Lucas Hollanda Oliveira, MD, MSc, Enia.
Isolated Wolff-Parkinson-White syndrome in identical twins
Fractionated electrograms with ST-segment elevation recorded from the human right ventricular outflow tract  Edward J. Vigmond, PhD, Igor R. Efimov, PhD,
B-cell lymphoma of the pericardium presenting with ventricular tachycardia with a successful catheter ablation  Takumi Yamada, MD, Franjo Siric, MD, Vishnu.
Jonathan T. Jaffe, MD, Lee-Gardie Jean, MD, Richard J. Murray, MD 
Pseudo typical atrial flutter occurring after cavotricuspid isthmus ablation in a patient with a prior history of Senning operation  Naoki Yoshida, MD,
Parasternal intercostal approach as an alternative to subxiphoid approach for epicardial catheter ablation: A case report  Koji Miyamoto, MD, Takashi.
Isolated, premature ventricular complex–induced right ventricular dysfunction mimicking arrhythmogenic right ventricular cardiomyopathy  Antonio Berruezo,
Finding the right pathway is the key to success
Direct endoscopic visualization of physiological His-bundle pacing and surrounding anatomy within reanimated human hearts using visible heart methodologies 
Catheter ablation of ventricular tachycardia in the setting of electrical storm after revascularization of a chronic total occlusion of the right coronary.
Kevin M. W. Leong, MBBS, MRCP, Henry Seligman, MBBS, MRCP, Amanda M
Recording of isolated very delayed potentials on the right ventricular epicardium in a patient with Brugada syndrome  Atsuyuki Watanabe, MD, Hiroshi Morita,
A case of ventricular fibrillation triggered by ventricular premature depolarizations exiting from different sites of the Purkinje network  Stavros E.
Nonobstructive septal hypertrophy in a young adult provoking recurrent polymorphic ventricular tachycardia successfully treated with transaortic and transventricular.
A case series and review of the literature regarding coronary artery complications associated with coronary sinus catheter ablation  Paul J. Garabelli,
Simrit K. Warring, MS, Heather N. Anderson, MD, J
Electroanatomical high-density mapping of different tachycardias in the right atrium after heart transplantation  Alexandra Schratter, MD, Valentina Schirripa,
Atrial Tachycardia in a Patient With Fabry’s Disease
Mapping of a postinfarction left ventricular aneurysm–dependent macroreentrant ventricular tachycardia  Elad Anter, MD, Jianqing Li, MD, Cory M. Tschabrunn,
Volume 10, Issue 1, Pages (January 2013)
Progressive electrical remodeling in apical hypertrophic cardiomyopathy leading to implantable cardioverter-defibrillator sensing failure during ventricular.
Radiofrequency ablation of common atrial flutter via right subclavian/jugular vein access in a patient with bilateral lower limb venous obstruction: Importance.
Brugada syndrome—Malignant phenotype associated with acute cardiac inflammation?  Anthony Li, MBBS, MD, Roderick Tung, MD, FHRS, Kalyanam Shivkumar, MD,
Hiroko Asakai, MD, Laura Fenwick, BSc, Robert M. Hamilton, MD, FRCP(C) 
Endocardial-only catheter ablation with substantial improvement in ventricular fibrillation recurrences in a patient with Brugada syndrome  Tatsuya Hayashi,
Successful catheter ablation of idiopathic ventricular tachycardia originating from the top of the left ventricular posterior papillary muscle near the.
Successful implantation of a subcutaneous cardiac defibrillator in a patient with a preexisting deep brain stimulator  Yousef Bader, MD, Jonathan Weinstock,
Atsuyuki Watanabe, MD, Atsuko Seki, MD, Michael C
Incremental value of electroanatomical mapping for the diagnosis of arrhythmogenic right ventricular cardiomyopathy in a patient with sustained ventricular.
IRX3 variant as a modifier of Brugada syndrome with frequent ventricular fibrillation  Yoshitaka Kimura, MD, Takeshi Aiba, MD, PhD, Tetsuo Sasano, MD,
Volume 9, Issue 1, Pages (January 2012)
Utility of entrainment pacing to clarify the circuit of macroreentrant tachycardia with dual early sites on activation maps  Koichi Nagashima, MD, PhD,
To eat, or not to eat…?: A live video case of swallowing-induced atrial tachycardia  Ben Corteville, MD, Daan Cottens, MD, Rene Tavernier, MD, PhD, Mattias.
Spastic occlusion of coronary artery during cryoballoon pulmonary vein isolation  Takashi Kaneshiro, MD, Yoshiyuki Matsumoto, MD, Minoru Nodera, MD, Masashi.
Different rate-dependent responses between J waves and the notches on an epicardial local electrogram in a patient with idiopathic ventricular fibrillation 
Abnormal epicardial electrophysiologic substrate in patients with early repolarization pattern and reduced left ventricular systolic function: A report.
Impact of a novel algorithm designed to reduce T-wave oversensing with the subcutaneous defibrillator in a patient with type I Brugada electrocardiogram 
A surgeon with symptomatic ventricular tachycardia while operating and exacerbated by left lateral decubitus position: Too much of a stretch?  Faris Khan,
Radiofrequency catheter ablation for treatment of premature ventricular contractions triggering ventricular fibrillation from the right ventricular outflow.
Nishaki Mehta, MD, Benjamin E. Peterson, MD, Roy M. John, MD, PhD 
Dana B. Gal, MD, Julianne Wojciak, MS, Jennifer Perera, MD, Ronn E
Lengthening the atrioventricular delay reduces large left atrial v waves and dyspnea after atrial fibrillation and tachycardia ablation  Raman Mitra,
Clinical problem solving: Maneuvering around a narrow complex tachycardia in a patient with Mustard repair for transposition of the great arteries  Nicholas.
Late atrial tachycardia originating from donor pulmonary vein in a double lung transplant recipient  Kumar Sanam, MD, Daniel Holmes, RCIS, CCT, Dipak.
Ablation of a symptomatic spontaneous automatic focus arising from an atriofascicular fiber  Sandrine Venier, MD, Paul Khairy, MD, PhD, Bernard Thibault,
Volume 13, Issue 1, Pages (January 2016)
Risen from the dead: Cardiac stereotactic ablative radiotherapy as last rescue in a patient with refractory ventricular fibrillation storm  Eberhard P.
Left ventricular pseudoaneurysm as a complication of left ventricular summit premature ventricular contraction ablation  Sanjay Dandamudi, MD, Susan S.
Percutaneous epicardial cryoablation of idiopathic premature ventricular contractions near the left anterior descending artery  Victor A. Abrich, MD,
Chance M. Witt, MD, Samuel J. Asirvatham, MD, FHRS, Carole A
HeartRhythm Case Reports
Presentation transcript:

Local activation delay exacerbates local J-ST elevation in the epicardium: Electrophysiological substrate in Brugada syndrome  Naoya Kataoka, MD, PhD, Satoshi Nagase, MD, PhD, Tsukasa Kamakura, MD, PhD, Takashi Noda, MD, PhD, Takeshi Aiba, MD, PhD, Kengo Kusano, MD, PhD, FHRS  HeartRhythm Case Reports  Volume 3, Issue 12, Pages 595-598 (December 2017) DOI: 10.1016/j.hrcr.2017.10.005 Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 1 The relationship of unipolar ST elevation type with the bipolar voltage map (A) and the local activation time (LAT) map (B) and surface electrocardiogram (ECG) (C) before the administration of pilsicainide. A: The unipolar electrogram reveals saddleback-type ST elevation in the middle level of the right ventricular outflow tract (RVOT) and coved-type ST elevation in the high level of the RVOT. There is no obvious relationship between ST elevation type and bipolar voltage. Representative bipolar and unipolar electrograms are shown in each of the ST elevation types. B: ST elevation type clearly relates to prolonged LAT in the RVOT. C: Surface ECG on the standard position and V1 and V2 on the third and second intercostal spaces (3ics and 2ics, respectively) before pilsicainide administration. No–ST elevation type is shown as a green tag, saddleback-type is shown as a yellow tag, and coved-type is shown as a pink tag in panels A and B. LAD = left anterior descending artery; TA = tricuspid annulus. HeartRhythm Case Reports 2017 3, 595-598DOI: (10.1016/j.hrcr.2017.10.005) Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 2 The relationship of unipolar ST elevation type with the bipolar voltage map (A) and the local activation time (LAT) map (B) and surface electrocardiogram (ECG) (C) after the administration of pilsicainide. A: The unipolar electrogram shows both saddleback-type and convex-type ST elevation in the middle level of the right ventricular outflow tract (RVOT), coved-type ST elevation in the tricuspid annulus, and convex-type ST elevation in the high level of the RVOT. Representative bipolar and unipolar electrograms are shown for each of the ST elevation types. B: The prolonged LAT zone in the low-voltage area of ≤0.5 mV (shown in A) shows coved- or convex-type ST elevation. C: Surface ECG after pilsicainide administration. Convex-type is shown as a red tag. Other colored dots are the same as those described in Figure 1. HeartRhythm Case Reports 2017 3, 595-598DOI: (10.1016/j.hrcr.2017.10.005) Copyright © 2017 Heart Rhythm Society Terms and Conditions

Figure 3 The relationship between local activation time (LAT) and local unipolar ST elevation at the timing of J point (J-ST) and 40 ms after J-point (J40-ST) in lead V5. A: Before the administration of pilsicainide. LAT is positively correlated with J-ST, the regression line y = 0.02x − 1.26, r = 0.84, P < .01, and n = 50. B: Before the administration of pilsicainide. J40-ST is also positively correlated with LAT, the regression line y = 0.01x − 0.48, r = 0.77, P < .01, and n = 50. C: After the administration of pilsicainide. LAT is positively correlated with J-ST, the regression line y = 0.01x − 0.25, r = 0.50, P < .01, and n = 40. D: After the administration of pilsicainide. J40-ST has no relationship with LAT, n = 40. Colored dots are the same as those described in Figures 1 and 2. HeartRhythm Case Reports 2017 3, 595-598DOI: (10.1016/j.hrcr.2017.10.005) Copyright © 2017 Heart Rhythm Society Terms and Conditions