Histologic atherosclerotic plaque characteristics are associated with restenosis rates after endarterectomy of the common and superficial femoral arteries

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Presentation transcript:

Histologic atherosclerotic plaque characteristics are associated with restenosis rates after endarterectomy of the common and superficial femoral arteries Wouter J.M. Derksen, MD, Jean-Paul P.M. de Vries, MD, PhD, Aryan Vink, MD, PhD, Evelyn Velema, MSc, Jan-Albert Vos, MD, PhD, Dominique de Kleijn, PhD, Frans L. Moll, MD, PhD, Gerard Pasterkamp, MD, PhD Journal of Vascular Surgery Volume 52, Issue 3, Pages 592-599 (September 2010) DOI: 10.1016/j.jvs.2010.03.063 Copyright © 2010 Society for Vascular Surgery Terms and Conditions

Fig 1 Treatment protocol of patients with peripheral leg ischemia when conservative treatment failed. In both hospitals, patients with peripheral leg ischemia are being treated according to the same protocol. The red boxes in the diagram are the studied patients. CFA, Common femoral artery; CFAE, common femoral artery endarterectomy; GSV, great saphenous vein; PI, percutanous intervention; RSFAE, remote superficial femoral artery endarterectomy; SFA, supficial femoral artery; TASC, TransAtlantic Inter-Society Consensus. Journal of Vascular Surgery 2010 52, 592-599DOI: (10.1016/j.jvs.2010.03.063) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

Fig 2 Plaque characteristics in relation to restenosis. Different plaque characteristics in relation to restenosis after endarterectomy of the femoral arteries. A, collagen; (B) lipid core; (C) macrophages; (D) smooth muscle cells; (E) calcification; (F) intraplaque hemorrhage. *P < .001. Journal of Vascular Surgery 2010 52, 592-599DOI: (10.1016/j.jvs.2010.03.063) Copyright © 2010 Society for Vascular Surgery Terms and Conditions

Fig 3 Plaque characteristics in relation to operation (common femoral artery endarterectomy [CFAE] or remote superficial femoral artery endarterectomy [RSFAE]). Different plaque characteristics for the common femoral artery (CFA) and the superficial femoral artery (SFA). A, lipid core; (B) intraplaque hemorrhage; (C) calcification; (D) collagen; (E) smooth muscle cells; and (F) macrophages. *P < .001. Journal of Vascular Surgery 2010 52, 592-599DOI: (10.1016/j.jvs.2010.03.063) Copyright © 2010 Society for Vascular Surgery Terms and Conditions