Outcomes after mechanical aortic valve replacement in children and young adults with congenital heart disease Patrick O. Myers, MD, Suyog A. Mokashi,

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Presentation transcript:

Outcomes after mechanical aortic valve replacement in children and young adults with congenital heart disease Patrick O. Myers, MD, Suyog A. Mokashi, MD, Edward Horgan, PA-C, Michele Borisuk, MSN, John E. Mayer, MD, Pedro J. del Nido, MD, Christopher W. Baird, MD The Journal of Thoracic and Cardiovascular Surgery Volume 157, Issue 1, Pages 329-340 (January 2019) DOI: 10.1016/j.jtcvs.2018.08.077 Copyright © 2018 Terms and Conditions

Figure 1 Kaplan-Meier estimates of survival. A, Unstratified. B, Stratified by valve type. The median follow-up was 5 years (interquartile range, 1.6-9.2 years; 600.2 patient-years), specifically 6.1 years for patients with a St Jude valve (St Jude Medical Inc, St Paul, Minn), 3.9 years with an On-X valve (On-X Life Technologies Inc, Austin, Tex), and 8.6 years with a CarboMedics valve (Sorin, SpA, Milan, Italy). CI, Confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 329-340DOI: (10.1016/j.jtcvs.2018.08.077) Copyright © 2018 Terms and Conditions

Figure 2 Freedom from reoperation. A, Freedom from aortic valve reoperation was 98% ± 1.3% at 1 and 5 years, 91.4% ± 3.9% at 7 years, and 78.3% ± 6.9% at 10 years to latest follow-up. B, Freedom from aortic valve reoperation was significantly better with the On-X valve (On-X Life Technologies Inc, Austin, Tex) (P < .001). CI, Confidence interval. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 329-340DOI: (10.1016/j.jtcvs.2018.08.077) Copyright © 2018 Terms and Conditions

Figure 3 Freedom from reoperation stratified by valve size. Valve sizes of 16 to 17 mm had a significantly higher risk of reoperation compared to larger valves of 19 to 27 mm. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 329-340DOI: (10.1016/j.jtcvs.2018.08.077) Copyright © 2018 Terms and Conditions

Freedom from aortic valve reoperation. The Journal of Thoracic and Cardiovascular Surgery 2019 157, 329-340DOI: (10.1016/j.jtcvs.2018.08.077) Copyright © 2018 Terms and Conditions