Rapid diagnostic testing of methicillin-resistant Staphylococcus aureus carriage at different anatomical sites: costs and benefits of less extensive screening.

Slides:



Advertisements
Similar presentations
Models for the organisation of hospital infection control and prevention programmes B. Gordts Clinical Microbiology and Infection Volume 11, Pages
Advertisements

P.-Y. Lévy  Clinical Microbiology and Infection 
Gram-positive infections: lessons learnt and novel solutions
Detection of Panton–Valentine leukocidin gene in Staphylococcus aureus by LightCycler PCR: clinical and epidemiological aspects  D. Johnsson, P. Mölling,
New epidemiology of Staphylococcus aureus infection in Asia
The use of Raman spectroscopy in the epidemiology of methicillin-resistant Staphylococcus aureus of human- and animal-related clonal lineages  M.W.H.
Clinical impact of a real-time PCR assay for rapid identification of Staphylococcus aureus and determination of methicillin resistance from positive blood.
G. Cornaglia, A. Lönnroth, M. Struelens 
M.F.Q. Kluytmans-VandenBergh, J.A.J.W. Kluytmans 
Staphylococcus aureus colonization at ICU admission as a risk factor for developing S. aureus ICU pneumonia  F.P. Paling, M. Wolkewitz, L.G.M. Bode, P.M.C.
Molecular characterization of methicillin-resistant Staphylococcus aureus isolated over a 2-year period in a Qatari hospital from multinational patients 
Effectiveness of a hospital-wide selective screening programme for methicillin-resistant Staphylococcus aureus (MRSA) carriers at hospital admission to.
European perspective and update on the management of nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus after more than 10 years.
The efficacy and safety of daptomycin: first in a new class of antibiotics for Gram- positive bacteria  M.J. Rybak  Clinical Microbiology and Infection 
European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after.
Detection of Panton–Valentine leukocidin gene in Staphylococcus aureus by LightCycler PCR: clinical and epidemiological aspects  D. Johnsson, P. Mölling,
E. Lindberg, I. Adlerberth, A.E. Wold 
Clinical impact of antibiotic-resistant Gram-positive pathogens
Cost-effectiveness of universal MRSA screening on admission to surgery
Clonal complex 398 methicillin-susceptible Staphylococcus aureus bloodstream infections are associated with high mortality  K. Bouiller, H. Gbaguidi-Haore,
European perspective and update on the management of complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus after.
Antimicrobial drug use and infection control practices associated with the prevalence of methicillin-resistant Staphylococcus aureus in European hospitals 
Cost analysis of a hospital-wide selective screening programme for methicillin-resistant Staphylococcus aureus (MRSA) carriers in the context of diagnosis.
Use of surveillance cultures and enteral vancomycin to control methicillin-resistant Staphylococcus aureus in a paediatric intensive care unit  K. Thorburn,
W. Witte, B. Pasemann, C. Cuny  Clinical Microbiology and Infection 
A multicentre analysis of epidemiology of the nosocomial bloodstream infections in Japanese university hospitals  M. Nagao  Clinical Microbiology and.
Vector control: a cornerstone in the malaria elimination campaign
Rapid genotyping of methicillin-resistant Staphylococcus aureus (MRSA) isolates using miniaturised oligonucleotide arrays  S. Monecke, R. Ehricht  Clinical.
Do we need new antibiotics?
Spa typing directly from a mecA, spa and pvl multiplex PCR assay—a cost-effective improvement for methicillin-resistant Staphylococcus aureus surveillance 
A new multiplex PCR for easy screening of methicillin-resistant Staphylococcus aureus SCCmec types I–V  K. Boye, M.D. Bartels, I.S. Andersen, J.A. Møller,
Dynamics of methicillin-resistant Staphylococcus aureus and methicillin-susceptible Staphylococcus aureus carriage in pig farmers: a prospective cohort.
Low prevalence of methicillin-resistant Staphylococcus aureus with reduced susceptibility to glycopeptides in Belgian hospitals  C. Nonhoff, O. Denis,
Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience.
A variant of the Southern German clone of methicillin-resistant Staphylococcus aureus is predominant in Croatia  A. Budimir, R.H. Deurenberg, Z. Bošnjak,
Bacterial resistance—the clinical challenge
Evaluation of three chromogenic media (MRSA-ID, MRSA-Select and CHROMagar MRSA) and ORSAB for surveillance cultures of methicillin-resistant Staphylococcus.
Diagnostic accuracy of culture-based and PCR-based detection tests for methicillin- resistant Staphylococcus aureus: a meta-analysis  J.M. Luteijn, G.A.A.
Body site colonization in patients with community-associated methicillin-resistant Staphylococcus aureus and other types of S. aureus skin infections 
Transmissibility of livestock-associated methicillin-resistant Staphylococcus aureus (ST398) in Dutch hospitals  M.W.M. Wassenberg, M.C.J. Bootsma, A.
M. Aires-de-Sousa  Clinical Microbiology and Infection 
Spread of Staphylococcus aureus clinical isolates carrying Panton–Valentine leukocidin genes during a 3-year period in Greece  V. Chini, E. Petinaki,
Characterisation of non-multiresistant methicillin-resistant Staphylococcus aureus (including EMRSA-15) in Kuwait Hospitals  E.E. Udo, N. Al-Sweih, B.
Y. Tveten, A. Jenkins, A.G. Allum, B.-E. Kristiansen 
Effectiveness of a hospital-wide selective screening programme for methicillin-resistant Staphylococcus aureus (MRSA) carriers at hospital admission to.
Antibacterial drug discovery in the 21st century
Methicillin-resistant Staphylococcus aureus (MRSA) with reduced susceptibility to glycopeptides (GISA) in 63 French general hospitals  G.L. Cartolano,
P.M. Hawkey  Clinical Microbiology and Infection 
Increased incidence of methicillin-resistant Staphylococcus aureus ST80, novel ST125 and SCCmecIV in the south-eastern part of Norway during a 12-year.
Rapid screening of methicillin-resistant Staphylococcus aureus using PCR and chromogenic agar: a prospective study to evaluate costs and effects  M.W.M.
Community-associated Staphylococcus aureus infections and nasal carriage among children: molecular microbial data and clinical characteristics  G. Sdougkos,
Sequential time to positivity of blood cultures can be a predictor of prognosis of patients with persistent Staphylococcus aureus bacteraemia  M.-S. Hsu,
G.M. Rossolini, E. Mantengoli  Clinical Microbiology and Infection 
Can pharmacokinetic–pharmacodynamic parameters provide dosing regimens that are less vulnerable to resistance?  P. Courvalin  Clinical Microbiology and.
Predictors of clinical and microbiological treatment failure in patients with methicillin- resistant Staphylococcus aureus (MRSA) bacteraemia: a retrospective.
Rise and subsequent decline of community-associated methicillin resistant Staphylococcus aureus ST30-IVc in Copenhagen, Denmark through an effective search.
Panton–Valentine leukocidin-encoding bacteriophage and gene sequence variation in community-associated methicillin-resistant Staphylococcus aureus  J.A.
Cost-effectiveness of adding decolonization to a surveillance strategy of screening and isolation for methicillin-resistant Staphylococcus aureus carriers 
J. Wilson, S. Elgohari, D. M. Livermore, B. Cookson, A. Johnson, T
A. Manzur, F. Gudiol  Clinical Microbiology and Infection 
W. Witte  Clinical Microbiology and Infection 
B.A. Cunha  Clinical Microbiology and Infection 
J.L. Balcázar  Clinical Microbiology and Infection 
G.C. Schito  Clinical Microbiology and Infection 
H. Ghasemzadeh-Moghaddam, V. Neela, W. van Wamel, R. A. Hamat, M
D.A. Robinson, M.C. Enright  Clinical Microbiology and Infection 
Staphylococcus aureus colonization at ICU admission as a risk factor for developing S. aureus ICU pneumonia  F.P. Paling, M. Wolkewitz, L.G.M. Bode, P.M.C.
Genetic diversity of community-associated methicillin-resistant Staphylococcus aureus in southern Stockholm,   H. Fang, G. Hedin, G. Li, C.E.
J. Segreti  Clinical Microbiology and Infection 
The future of diagnostic bacteriology
Presentation transcript:

Rapid diagnostic testing of methicillin-resistant Staphylococcus aureus carriage at different anatomical sites: costs and benefits of less extensive screening regimens  M.W.M. Wassenberg, J.A.J.W Kluytmans, R.W. Bosboom, A.G.M. Buiting, E.P.M. van Elzakker, W.J.G. Melchers, S.F.T. Thijsen, A. Troelstra, C.M.J.E Vandenbroucke-Grauls, C.E. Visser, A. Voss, P.F.G. Wolffs, M.W.H. Wulf, A.A. van Zwet, G.A. de Wit, M.J.M. Bonten  Clinical Microbiology and Infection  Volume 17, Issue 11, Pages 1704-1710 (November 2011) DOI: 10.1111/j.1469-0691.2011.03502.x Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 1 Costs per isolation day avoided for multiple site testing without conventional back-up cultures. RDT, rapid diagnostic testing. Clinical Microbiology and Infection 2011 17, 1704-1710DOI: (10.1111/j.1469-0691.2011.03502.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions

FIG. 2 Costs per isolation day avoided for RDT testing without back-up cultures using BD GeneOhm™ MRSA PCR (a), Xpert MRSA assay (b) and chromogenic agar (c). RDT, rapid diagnostic testing. Clinical Microbiology and Infection 2011 17, 1704-1710DOI: (10.1111/j.1469-0691.2011.03502.x) Copyright © 2011 European Society of Clinical Infectious Diseases Terms and Conditions