Reference Andrea Magdechová Vendula Frechová ALKALOIDS Reference Andrea Magdechová Vendula Frechová Chem-465 4/28/2019

Characteristic Nitrogen in heterocyclic ring Synthesized by plants, animal, fungi Pharmacological effects Bitter taste Poisonous Analgesics 4/28/2019 Chem-465

Chemistry Colourless Crystalline Non – volatile solids are soluble in organic solvent Insoluble in water 4/28/2019 Chem-465

Classified Biological activity Chemical structure Biosynthetic pathway 4/28/2019 Chem-465

Amphetamine Club drug Performance enhancer Prescription to treat: attention – deficit hyperactivity disorder in adults and children 4/28/2019 Chem-465

Ephedrine Stimulant Appetite suppressant Helps studying, thinking or concentration 4/28/2019 Chem-465

Caffeine Acts as psychoactive stimulant and diuretic in humans Guaranine found in guarana, mateine in mate, theine in tea Extracted from beans of the coffee plant and leaves of the tea bush Tea contains half as much of caffeine as coffe Chocolate contains a small amount of caffeine 4/28/2019 Chem-465

CAFFEINE PER SERVING [mg] PRODUCT SERVING SIZE [ml] CAFFEINE PER SERVING [mg] Brewed coffe 240 135 Coffe espresso 57 100 Red bull 250 80 Bag of tea 50 Coca - cola 355 34 Green tea Decaffeinated coffe 5 4/28/2019 Chem-465

Nicotine Found in the nightshade family of plants Tobacco, tomato, potato, eggplant Hygroscopic, oily liquid Feelings of relaxation, calmness, alertness Enhances concentration, learning and memory Cigarettes contain 0,1 to 2,8 mg of nicotine (Nightshade = lilkovité) 4/28/2019 Chem-465

Caffeine, nicotine Chem-465 4/28/2019