Preoperative levosimendan infusion in combined aortic valve and coronary bypass surgery H Leppikangas, K Järvelä, T Sisto, P Maaranen, M Virtanen, P.

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Presentation transcript:

Preoperative levosimendan infusion in combined aortic valve and coronary bypass surgery H Leppikangas, K Järvelä, T Sisto, P Maaranen, M Virtanen, P Lehto, S Karlsson, T Kööbi, L Lindgren British Journal of Anaesthesia Volume 106, Issue 3, Pages 298-304 (March 2011) DOI: 10.1093/bja/aeq402 Copyright © 2011 The Author(s) Terms and Conditions

Fig 1 (a) SI, (b) CI, and (c) HR at baseline (−1), on the morning of surgery (0), and on the first (1) and fourth (4) postoperative mornings, measured by whole-body impedance cardiography. Results are expressed as mean (confidence intervals). *P<0.05 between the groups and # the significant difference between the groups from the first postoperative morning to the morning before surgery. British Journal of Anaesthesia 2011 106, 298-304DOI: (10.1093/bja/aeq402) Copyright © 2011 The Author(s) Terms and Conditions

Fig 2 (a) E/E′ and (b) LVEF at baseline and on the first and fourth postoperative mornings. Results are expressed as mean (sem). *P<0.05 for the change in LVEF between the groups from baseline to the fourth postoperative morning. British Journal of Anaesthesia 2011 106, 298-304DOI: (10.1093/bja/aeq402) Copyright © 2011 The Author(s) Terms and Conditions

Fig 3 The concentration of levosimendan, OR-1855, and OR-1896 24, 48, 72, and 96 h after the start of levosimendan infusion. The operation started at 24 h. British Journal of Anaesthesia 2011 106, 298-304DOI: (10.1093/bja/aeq402) Copyright © 2011 The Author(s) Terms and Conditions

Fig 4 ECW at baseline (−1), on the morning of surgery (0), and on the first (1) and fourth (4) postoperative mornings. Results are expressed as mean (sem). *P<0.05 between the groups. British Journal of Anaesthesia 2011 106, 298-304DOI: (10.1093/bja/aeq402) Copyright © 2011 The Author(s) Terms and Conditions