Comparison of changes in electroencephalographic measures during induction of general anaesthesia: influence of the gamma frequency band and electromyogram.

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Comparison of changes in electroencephalographic measures during induction of general anaesthesia: influence of the gamma frequency band and electromyogram signal  J.W. Sleigh, D.A. Steyn-Ross, M.L. Steyn-Ross, M.L. Williams, P. Smith  British Journal of Anaesthesia  Volume 86, Issue 1, Pages 50-58 (January 2001) DOI: 10.1093/bja/86.1.50 Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 1 Comparison of typical power spectra of the raw EEG signal with that of the first time-derivative of the same 1 s segment of the EEG signal in an awake patient. The spectral power density of the raw EEG (left) is in units of (μV)2 Hz−1 and that of the first derivative (right) in units of (μVs−1)2 Hz−1. The signal has been digitally band-pass filtered 0.1 to 47 Hz. British Journal of Anaesthesia 2001 86, 50-58DOI: (10.1093/bja/86.1.50) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 2 Pictorial representation of how the power spectrum of the observed EEG signal (EEGscalp) consists of the sum of power spectra of the frontalis EMG signal (EMGfrontalis) and that of the true EEG signal (EEGtrue). British Journal of Anaesthesia 2001 86, 50-58DOI: (10.1093/bja/86.1.50) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 3 Example of the power spectra of the submental EMG signal and scalp EEG from an awake patient. The EMGfrontalis signal cannot be measured directly, but is in fact the same EMGsubmental signal suitably scaled to give a diagrammatic representation of the various ratios as described in the text. The unit of spectral power is (μV)2 Hz−1. British Journal of Anaesthesia 2001 86, 50-58DOI: (10.1093/bja/86.1.50) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 4 Graphs showing typical changes in EEG indices (BIS, SE50d, SE50d30Hz and BetaRatio) with time for a single volunteer. TLOC is the time of loss of consciousness and R is the time of reawakening. British Journal of Anaesthesia 2001 86, 50-58DOI: (10.1093/bja/86.1.50) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions

Fig 5 Typical changes in various EEG variables in a single patient during induction of anaesthesia. The vertical dotted line in each graph indicates the time of loss of consciousness. BIS, BetaRatio and SynchFastSlow are dimensionless ratios. The units of EMG power (d) are dB relative to 1(μV)2 Hz−1. The total power is the log10 of the volume under the bispectral surface from 0.5 to 47 Hz, and the high power is the logarithm of the volume under the bispectral surface from 40 to 47 Hz. See text for detailed description of the calculation of each variable. British Journal of Anaesthesia 2001 86, 50-58DOI: (10.1093/bja/86.1.50) Copyright © 2001 British Journal of Anaesthesia Terms and Conditions