Validation of the PIII CLI risk score for the prediction of amputation-free survival in patients undergoing infrainguinal autogenous vein bypass for critical.

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Presentation transcript:

Validation of the PIII CLI risk score for the prediction of amputation-free survival in patients undergoing infrainguinal autogenous vein bypass for critical limb ischemia Andres Schanzer, MD, Philip P. Goodney, MD, MS, Youfu Li, MD, MPH, Mohammad Eslami, MD, Jack Cronenwett, MD, Louis Messina, MD, Michael S. Conte, MD Journal of Vascular Surgery Volume 50, Issue 4, Pages 769-775 (October 2009) DOI: 10.1016/j.jvs.2009.05.055 Copyright © 2009 Society for Vascular Surgery Terms and Conditions

Fig 1 Score card. PIII, PREVENT III; HCT, hematocrit; CAD, coronary artery disease. Journal of Vascular Surgery 2009 50, 769-775DOI: (10.1016/j.jvs.2009.05.055) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

Fig 2 Kaplan-Meier curves demonstrating amputation-free (AF) survival stratified according to each patient's calculated risk score (Vascular Study Group of Northern New England [VSGNNE] cohort). Journal of Vascular Surgery 2009 50, 769-775DOI: (10.1016/j.jvs.2009.05.055) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

Fig 3 Validation of the PREVENT III (PIII) critical limb ischemia (CLI) risk score in 4 different datasets (3286 patients)—PIII derivation set, PIII validation set, retrospective validation set, prospective Vascular Study Group of Northern New England (VSGNNE) validation set. AF, Amputation-free. Journal of Vascular Surgery 2009 50, 769-775DOI: (10.1016/j.jvs.2009.05.055) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

Fig 4 Risk category breakdown by predictor (Vascular Study Group of Northern New England [VSGNNE] cohort). CAD, Coronary artery disease. Journal of Vascular Surgery 2009 50, 769-775DOI: (10.1016/j.jvs.2009.05.055) Copyright © 2009 Society for Vascular Surgery Terms and Conditions

Fig 5 PREVENT III (PIII) critical limb ischemia (CLI) risk score was an effective tool for discriminating three significant strata of risk when tested on the following endpoints: perioperative major adverse cardiac event (MACE) (a), perioperative and 1-year mortality (b), and 1-year ability to ambulate (c). Journal of Vascular Surgery 2009 50, 769-775DOI: (10.1016/j.jvs.2009.05.055) Copyright © 2009 Society for Vascular Surgery Terms and Conditions