Ultrasound-guided regional anesthesia for carotid endarterectomy induces early hemodynamic and stress hormone changes Judith Hoefer, MD, MSc, Eve Pierer,

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Presentation transcript:

Ultrasound-guided regional anesthesia for carotid endarterectomy induces early hemodynamic and stress hormone changes Judith Hoefer, MD, MSc, Eve Pierer, MD, Barbara Rantner, MD, Karl-Heinz Stadlbauer, MD, Gustav Fraedrich, MD, Josef Fritz, Dipl Ing, Axel Kleinsasser, MD, Corinna Velik-Salchner, MD Journal of Vascular Surgery Volume 62, Issue 1, Pages 57-67 (July 2015) DOI: 10.1016/j.jvs.2015.02.036 Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 1 Study flow chart. GA, General anesthesia; RA, locoregional anesthesia; t, time. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 2 Consolidated Standards of Reporting Trials (CONSORT) flow diagram. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 3 Intraoperative systolic blood pressure (SBP) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. *P < .05, **P < .001; NS, Not significant. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 4 Heart rate (HR) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. **P < .001; NS, Not significant. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 5 Plasma cortisol (normal values are shaded) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. *P < .05, **P < .001; NS, Not significant. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 6 Plasma metanephrine (normal values are shaded) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. No differences between groups were detected. NS, Not significant. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 7 Plasma normetanephrine (normal values are shaded) in patients undergoing carotid endarterectomy (CEA) with regional anesthesia (RA) or general anesthesia (GA) at baseline (t0), after induction of anesthesia (t1), before cross-clamping (t2), after cross-clamping (t3), and 1 hour after admission to the postanesthesia care unit (t4). Data are presented as mean ± standard deviation. No differences between groups were detected. NS, Not significant. Journal of Vascular Surgery 2015 62, 57-67DOI: (10.1016/j.jvs.2015.02.036) Copyright © 2015 Society for Vascular Surgery Terms and Conditions