The PPAR-α agonist GW7647 reduces experimentally induced myopia.

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The PPAR-α agonist GW7647 reduces experimentally induced myopia. The PPAR-α agonist GW7647 reduces experimentally induced myopia. The effect of 63- and 189-μg intravitreal injections of GW7647 on the ocular axial length of LIM animals is shown: both the 63-μg (n = 8) and 189-μg injections (n = 8) of GW7647 significantly reduce myopia as compared with control (n = 7). * indicates that a group is significantly different from the controls with p < 0.05 using Student’s t test. Eric Bertrand et al. Mol Cell Proteomics 2006;5:2158-2166 © 2006 The American Society for Biochemistry and Molecular Biology