Renal Replacement Therapy in Acute Kidney Injury

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Presentation transcript:

Renal Replacement Therapy in Acute Kidney Injury Paul M. Palevsky Advances in Chronic Kidney Disease Volume 20, Issue 1, Pages 76-84 (January 2013) DOI: 10.1053/j.ackd.2012.09.004 Copyright © 2013 Terms and Conditions

Figure 1 Forrest plot of pooled odds ratios for mortality of studies comparing early to late initiation of renal replacement therapy published between 1985 and July 2010. Using a random effects model, the calculated pooled odds ratio is 0.45 (95% confidence interval [CI], 0.28-0.72). Reprinted with permission from Karvellas CJ, Farhat MR, Sajjad I, et al. A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Crit Care 2011;15:R72. Advances in Chronic Kidney Disease 2013 20, 76-84DOI: (10.1053/j.ackd.2012.09.004) Copyright © 2013 Terms and Conditions

Figure 2 Forrest plot of pooled odds ratios for mortality from 9 randomized trials comparing intermittent renal replacement therapy (IRRT) to continuous renal replacement therapy (CRRT). Using a random effects model, the calculated pooled odds ratio is 0.99 (95% confidence interval [CI], 0.78-1.26). Reprinted with permission from Bagshaw SM, Berthiaume LR, Delaney A, Bellomo R. Continuous versus intermittent renal replacement therapy for critically ill patients with acute kidney injury: a meta-analysis. Crit Care Med 2008;36:610-617. Advances in Chronic Kidney Disease 2013 20, 76-84DOI: (10.1053/j.ackd.2012.09.004) Copyright © 2013 Terms and Conditions