Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative

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Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative W. Wirth, S. Larroque, R.Y. Davies, M. Nevitt, A. Gimona, F. Baribaud, J.H. Lee, O. Benichou, B.T. Wyman, M. Hudelmaier, S. Maschek, F. Eckstein Osteoarthritis and Cartilage Volume 19, Issue 1, Pages 74-83 (January 2011) DOI: 10.1016/j.joca.2010.10.022 Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Image acquisition protocols and anatomical subregions analyzed: (a) Coronal FLASH with water excitation (b) Sagittal DESS with water excitation (c) Tibial cartilage viewed from superior: (MT=medial tibia, LT=lateral tibia; c=central, e=external, i=internal, a=anterior, and p=posterior) (d) Weight-bearing femoral cartilage viewed from inferior: cMF=weight-bearing (central) medial femoral cartilage, cLF=weight-bearing (central) lateral femoral cartilage; c=central, e=external, i=internal, Osteoarthritis and Cartilage 2011 19, 74-83DOI: (10.1016/j.joca.2010.10.022) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Longitudinal change in cartilage thickness (in μm) between BL and Y1 and between Y1 and Y2. (a) and (c) Coronal FLASH sample (n=239); (b) and (d) Sagittal DESS sample (n=107) sample Graphs (a) and (b) show the change in the MT (dark continuous line) and in the LT (light continuous line), as well as in the weight-bearing (central) part of the medial femoral condyle (dark dashed line) and in the lateral femoral condyle (light dashed line) Graphs (c) and (d) show the change in the 16 OVs (OV1–OV16), from bottom to top. Osteoarthritis and Cartilage 2011 19, 74-83DOI: (10.1016/j.joca.2010.10.022) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Scatterplot of the change in cartilage thickness (in μm) between BL and Y1 and between Y1 and Y2. (a) and (c) Coronal FLASH sample (n=239); (b) and (d) Sagittal DESS sample (n=107) sample. Graphs (a) und (b) illustrate the change in the MFTC Graphs (c) und (d) illustrate the change in the subregion with the largest changes in each participants (OV 1). Osteoarthritis and Cartilage 2011 19, 74-83DOI: (10.1016/j.joca.2010.10.022) Copyright © 2010 Osteoarthritis Research Society International Terms and Conditions