Volume 136, Issue 5, Pages 1629-1638 (May 2009) A 28-Year Study of the Course of Hepatitis Δ Infection: A Risk Factor for Cirrhosis and Hepatocellular Carcinoma  Raffaella Romeo, Ersilio Del Ninno, Mariagrazia Rumi, Antonio Russo, Angelo Sangiovanni, Roberto de Franchis, Guido Ronchi, Massimo Colombo  Gastroenterology  Volume 136, Issue 5, Pages 1629-1638 (May 2009) DOI: 10.1053/j.gastro.2009.01.052 Copyright © 2009 AGA Institute Terms and Conditions

Figure 1 Demographic characteristics and modality of diagnosis of the 299 patients at entry. Gastroenterology 2009 136, 1629-1638DOI: (10.1053/j.gastro.2009.01.052) Copyright © 2009 AGA Institute Terms and Conditions

Figure 2 (A) Outcome of patients who did not receive antiviral treatment. BL, baseline; SVR, sustained virologic response. (B) Outcome of patients treated with interferon. (C) Outcome of patients treated with corticosteroids. Gastroenterology 2009 136, 1629-1638DOI: (10.1053/j.gastro.2009.01.052) Copyright © 2009 AGA Institute Terms and Conditions

Figure 3 Clinical outcome of the 299 patients during a mean follow-up of 233 months. Gastroenterology 2009 136, 1629-1638DOI: (10.1053/j.gastro.2009.01.052) Copyright © 2009 AGA Institute Terms and Conditions

Figure 4 (A) Cumulative probability of developing cirrhosis in the 299 patients enrolled into the study. (B) Cumulative probability of developing clinical decompensation in the 186 cirrhotic patients followed for a mean of 125 (range, 12–468) months from cirrhosis development. (C) Cumulative probability of developing hepatocellular carcinoma in 299 patients over a mean observation of 233 (range, 8–516) months. Gastroenterology 2009 136, 1629-1638DOI: (10.1053/j.gastro.2009.01.052) Copyright © 2009 AGA Institute Terms and Conditions