Bay induces aberrant assembly of Cp

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Bay 38-7690 induces aberrant assembly of Cp Bay 38-7690 induces aberrant assembly of Cp. (A) Purified HBV C150 (18 µM dimer) was assembled in the presence of DMSO or 10 µM Bay 38-7690 and analyzed by TEM. Bars, 50 nm. Bay 38-7690 induces aberrant assembly of Cp. (A) Purified HBV C150 (18 µM dimer) was assembled in the presence of DMSO or 10 µM Bay 38-7690 and analyzed by TEM. Bars, 50 nm. (B) C150 (7.5 µM dimer) was assembled in the presence of 0 to 50 µM Bay 38-7690 and analyzed by DLS. Results were plotted using GraphPad Prism 5.0 and analyzed with the “log(agonist) versus normalized response − variable slope” equation. The values represent mean ± standard error of the mean from two independent experiments. Andrew D. Huber et al. mSphere 2018; doi:10.1128/mSphereDirect.00131-18