Genetic Investigation of Quantitative Traits Related to Autism: Use of Multivariate Polygenic Models with Ascertainment Adjustment Yun Ju Sung, Geraldine.

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Genetic Investigation of Quantitative Traits Related to Autism: Use of Multivariate Polygenic Models with Ascertainment Adjustment Yun Ju Sung, Geraldine Dawson, Jeffrey Munson, Annette Estes, Gerard D. Schellenberg, Ellen M. Wijsman The American Journal of Human Genetics Volume 76, Issue 1, Pages 68-81 (January 2005) DOI: 10.1086/426951 Copyright © 2005 The American Society of Human Genetics Terms and Conditions

Figure 1 Covariate effects (age and sex) for social motivation when estimates with ascertainment adjustment are used. Solid and dashed lines represent males and females, respectively. The vertical dotted line indicates age 18 years. The American Journal of Human Genetics 2005 76, 68-81DOI: (10.1086/426951) Copyright © 2005 The American Society of Human Genetics Terms and Conditions

Figure 2 Box plots for IQ and age-and-sex–adjusted BPASS traits. A = 297 affected children; U = 54 unaffected children; P = 343 parents. Each box shows lower quartile, median, and upper quartile. The whiskers extend to the most extreme data point that is no more than 1.5 times the interquartile range from the box. The American Journal of Human Genetics 2005 76, 68-81DOI: (10.1086/426951) Copyright © 2005 The American Society of Human Genetics Terms and Conditions