Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's.

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Presentation transcript:

Extensively hydrolyzed casein formula containing Lactobacillus rhamnosus GG reduces the occurrence of other allergic manifestations in children with cow's milk allergy: 3-year randomized controlled trial  Roberto Berni Canani, MD, PhD, Margherita Di Costanzo, MD, Giorgio Bedogni, MD, Antonio Amoroso, BS, Linda Cosenza, MD, Carmen Di Scala, LDN, Viviana Granata, MD, Rita Nocerino, RN  Journal of Allergy and Clinical Immunology  Volume 139, Issue 6, Pages 1906-1913.e4 (June 2017) DOI: 10.1016/j.jaci.2016.10.050 Copyright © 2017 The Authors Terms and Conditions

Fig 1 Study design. Journal of Allergy and Clinical Immunology 2017 139, 1906-1913.e4DOI: (10.1016/j.jaci.2016.10.050) Copyright © 2017 The Authors Terms and Conditions

Fig 2 Flow of the children through the study. Journal of Allergy and Clinical Immunology 2017 139, 1906-1913.e4DOI: (10.1016/j.jaci.2016.10.050) Copyright © 2017 The Authors Terms and Conditions

Fig 3 Incidence of the main study outcome at CCA. Journal of Allergy and Clinical Immunology 2017 139, 1906-1913.e4DOI: (10.1016/j.jaci.2016.10.050) Copyright © 2017 The Authors Terms and Conditions

Fig 4 Incidence of CMA tolerance at CCA. Journal of Allergy and Clinical Immunology 2017 139, 1906-1913.e4DOI: (10.1016/j.jaci.2016.10.050) Copyright © 2017 The Authors Terms and Conditions

Fig E1 Exploratory analysis of the incidence of components of the main outcome (eczema, urticaria, asthma, and rhinoconjunctivitis) during the study period. Journal of Allergy and Clinical Immunology 2017 139, 1906-1913.e4DOI: (10.1016/j.jaci.2016.10.050) Copyright © 2017 The Authors Terms and Conditions

Fig E2 Incidence of SPT response negativization during the study period. Journal of Allergy and Clinical Immunology 2017 139, 1906-1913.e4DOI: (10.1016/j.jaci.2016.10.050) Copyright © 2017 The Authors Terms and Conditions