A randomized trial of vonapanitase (PATENCY-1) to promote radiocephalic fistula patency and use for hemodialysis Anthony J. Bleyer, MD, MS, Vincent A.

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Presentation transcript:

A randomized trial of vonapanitase (PATENCY-1) to promote radiocephalic fistula patency and use for hemodialysis Anthony J. Bleyer, MD, MS, Vincent A. Scavo, MD, Samuel E. Wilson, MD, Barry J. Browne, MD, Brian L. Ferris, MD, C. Keith Ozaki, MD, Timmy Lee, MD, Eric K. Peden, MD, Bradley S. Dixon, MD, Rick Mishler, MD, Timothy P. O'Connor, MD, Kendrah Kidd, MS, Steven K. Burke, MD Journal of Vascular Surgery Volume 69, Issue 2, Pages 507-515 (February 2019) DOI: 10.1016/j.jvs.2018.04.068 Copyright © 2018 The Authors Terms and Conditions

Journal of Vascular Surgery 2019 69, 507-515DOI: (10.1016/j.jvs.2018.04.068) Copyright © 2018 The Authors Terms and Conditions

Fig 1 Consolidated Standards of Reporting Trials diagram of patient flow through the study. AVF, Arteriovenous fistula. Journal of Vascular Surgery 2019 69, 507-515DOI: (10.1016/j.jvs.2018.04.068) Copyright © 2018 The Authors Terms and Conditions

Fig 2 A, Kaplan-Meier estimates of fistula primary patency. Primary patency was lost at the time of the first occurrence of fistula thrombosis or procedure to restore or to maintain fistula patency. B, Kaplan-Meier estimates of fistula secondary patency. Secondary patency was lost at the time of fistula abandonment. Journal of Vascular Surgery 2019 69, 507-515DOI: (10.1016/j.jvs.2018.04.068) Copyright © 2018 The Authors Terms and Conditions

Fig 3 The proportions of patients with use of the fistula for hemodialysis and unassisted use of the fistula for hemodialysis. Unassisted meant there was no corrective procedure (eg, balloon angioplasty or surgical revision) before use. Journal of Vascular Surgery 2019 69, 507-515DOI: (10.1016/j.jvs.2018.04.068) Copyright © 2018 The Authors Terms and Conditions