Pre-radiographic osteoarthritic changes are highly prevalent in the medial patella and medial posterior femur in older persons: Framingham OA study D.

Slides:

Advertisements

Similar presentations

C. G Peterfy, M. D. Ph. D. , A Guermazi, M. D. , S Zaim, M. D. , P. F

Advertisements

Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study J.J. Stefanik,

Whole joint MRI assessment of surgical cartilage repair of the knee: Cartilage Repair OsteoArthritis Knee Score (CROAKS) F.W. Roemer, A. Guermazi, S.

Figure 1 Imaging of a painful knee using radiography and MRI

MRI-detected subchondral bone marrow signal alterations of the knee joint: terminology, imaging appearance, relevance and radiological differential diagnosis

Subregional laminar cartilage MR spin–spin relaxation times (T2) in osteoarthritic knees with and without medial femorotibial cartilage loss – data from.

Validity and responsiveness of a new measure of knee osteophytes for osteoarthritis studies: data from the osteoarthritis initiative M. Hakky, M. Jarraya,

A narrative overview of the current status of MRI of the hip and its relevance for osteoarthritis research – what we know, what has changed and where.

Atlas of individual radiographic features in osteoarthritis, revised

A. Guermazi, H. Alizai, M. D. Crema, S. Trattnig, R. R. Regatte, F. W

Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study F.W. Roemer, T. Neogi,

Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study J.J. Stefanik,

Imaging following acute knee trauma

Loss of anterior cruciate ligament integrity and the development of radiographic knee osteoarthritis: a sub-study of the osteoarthritis initiative V.L.

Osteoporosis increases the severity of cartilage damage in an experimental model of osteoarthritis in rabbits E. Calvo, M.D., S. Castañeda, M.D., R.

T1ρ and T2 relaxation times predict progression of knee osteoarthritis

Predictive validity of within-grade scoring of longitudinal changes of MRI-based cartilage morphology and bone marrow lesion assessment in the tibio-femoral.

Increased risk for radiographic osteoarthritis features in young active athletes: a cross- sectional matched case–control study F.W. Roemer, M. Jarraya,

Patellofemoral morphology and alignment: reference values and dose–response patterns for the relation to MRI features of patellofemoral osteoarthritis

Imaging of non-osteochondral tissues in osteoarthritis

C. G Peterfy, M. D. Ph. D. , A Guermazi, M. D. , S Zaim, M. D. , P. F

7th International Workshop on Osteoarthritis Imaging report: “imaging in OA – now is the time to move ahead” A. Guermazi, F. Eckstein, D. Hunter, F.

Intraoperative validation of quantitative T2 mapping in patients with articular cartilage lesions of the knee S.T. Soellner, A. Goldmann, D. Muelheims,

Reference values and Z-scores for subregional femorotibial cartilage thickness – results from a large population-based sample (Framingham) and comparison.

Cyst-like lesions of the knee joint and their relation to incident knee pain and development of radiographic osteoarthritis: the MOST study A. Guermazi,

Evolution of semi-quantitative whole joint assessment of knee OA: MOAKS (MRI Osteoarthritis Knee Score) D.J. Hunter, A. Guermazi, G.H. Lo, A.J. Grainger,

Bone marrow lesions, subchondral bone cysts and subchondral bone attrition are associated with histological synovitis in patients with end-stage knee.

The osteoarthritis initiative: report on the design rationale for the magnetic resonance imaging protocol for the knee C.G. Peterfy, M.D., Ph.D., E.

Complete anterior cruciate ligament tear and the risk for cartilage loss and progression of symptoms in men and women with knee osteoarthritis S. Amin,

Morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis of the knee S.H. Hwang, K.A. Jung, W.J. Lee, K.H. Yang,

Sensitivity to Change of 3D Meniscal Measures in Rapidly Progressing Knee Osteoarthritis and Association With Radiographic Joint Space Width Loss M.

Quantitatively-measured bone marrow lesions in the patellofemoral joint: distribution and association with pain C. Ratzlaff, R. Russell, J. Duryea Osteoarthritis.

Structural correlates of pain in joints with osteoarthritis

L. A. MacFarlane, H. Yang, J. E. Collins, A. Guermazi, M. H. Jones, E

Magnetic resonance imaging lesions are more severe and cartilage T2 relaxation time measurements are higher in isolated lateral compartment radiographic.

Volumetric and semiquantitative assessment of MRI-detected subchondral bone marrow lesions in knee osteoarthritis: a comparison of contrast-enhanced and.

Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA – data from the OA initiative

Whole joint MRI assessment of surgical cartilage repair of the knee: Cartilage Repair OsteoArthritis Knee Score (CROAKS) F.W. Roemer, A. Guermazi, S.

S. Reichenbach, M. D. , A. Guermazi, M. D. , J. Niu, M. B. B. S. , D

F. Eckstein, A. Guermazi, G. Gold, J. Duryea, M. -P

Hip Osteoarthritis MRI Scoring System (HOAMS): reliability and associations with radiographic and clinical findings F.W. Roemer, D.J. Hunter, A. Winterstein,

M. K. Javaid, J. A. Lynch, I. Tolstykh, A. Guermazi, F. Roemer, P

D. J. Hunter, D. P. Beavers, F. Eckstein, A. Guermazi, R. F. Loeser, B

Is increased joint loading detrimental to obese patients with knee osteoarthritis? A secondary data analysis from a randomized trial M. Henriksen, D.J.

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the dog J.L. Cook, K. Kuroki, D. Visco, J.-P.

D. Hayashi, F.W. Roemer, A. Guermazi Osteoarthritis and Cartilage

The association of prevalent medial meniscal pathology with cartilage loss in the medial tibiofemoral compartment over a 2-year period M.D. Crema, A.

Bone marrow lesions and joint effusion are strongly and independently associated with weight-bearing pain in knee osteoarthritis: data from the osteoarthritis.

Role of physical activity in cartilage damage progression of subjects with baseline full- thickness cartilage defects in medial tibiofemoral compartment:

Comments on Beattie et al

Baseline radiographic osteoarthritis and semi-quantitatively assessed meniscal damage and extrusion and cartilage damage on MRI is related to quantitatively.

F.W. Roemer, M.D. Osteoarthritis and Cartilage

Relevance of imaging in anti nerve growth factor inhibitor (aNGF) studies with a focus on eligibility and on-study safety – A pictorial overview F.W.

Magnetic resonance imaging (MRI)-defined cartilage degeneration and joint pain are associated with poor physical function in knee osteoarthritis – the.

Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.

Comparison of BLOKS and WORMS scoring systems part I

Spectrum of meniscal pathology in osteoarthritis revisited - from signal change to complete destruction. M. Jarraya, F.W. Roemer, M. Englund, M.D. Crema,

X. Li, Ph. D. , C. Benjamin Ma, M. D. , T. M. Link, M. D. , D. -D

Synovitis and the risk of knee osteoarthritis: the MOST Study

D. J. Hunter, N. Arden, F. Cicuttini, M. D. Crema, B. Dardzinski, J

Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis – data from the Osteoarthritis.

Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen.

Susceptibility artifacts detected on 3T MRI of the knee: frequency, change over time and associations with radiographic findings: data from the Joints.

Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study M.D. Crema, D.T. Felson, A. Guermazi,

Preliminary study on diffraction enhanced radiographic imaging for a canine model of cartilage damage C. Muehleman, Ph.D., J. Li, M.D., Z. Zhong, Ph.D.

The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies

Osteoarthritis and Cartilage

Osteoarthritis year 2012 in review: imaging

Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing – data from the Osteoarthritis Initiative K. Bloecker,

Association between bone marrow lesions detected by magnetic resonance imaging and knee pain in community residents in Korea I.J. Kim, D.H. Kim, J.Y.

Presentation transcript:

Pre-radiographic osteoarthritic changes are highly prevalent in the medial patella and medial posterior femur in older persons: Framingham OA study D. Hayashi, D.T. Felson, J. Niu, D.J. Hunter, F.W. Roemer, P. Aliabadi, A. Guermazi Osteoarthritis and Cartilage Volume 22, Issue 1, Pages 76-83 (January 2014) DOI: 10.1016/j.joca.2013.10.007 Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Flow chart for subject inclusion. Osteoarthritis and Cartilage 2014 22, 76-83DOI: (10.1016/j.joca.2013.10.007) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Subregions of the knee joint as defined by WORMS. Subregional division of the knee joint as defined by the WORMS system. The patella (left illustration) is divided into medial (M) and lateral (L) subregions in the axial plane. The patellar ridge is included in the medial compartment. Scoring of cartilage damage, bone marrow lesions, bone attrition, and subchondral cysts are based on these two subregions. Scoring of osteophytes was done at the four locations of the patella: medial edge and lateral edge (using the axial image), and superior pole and inferior pole (using the sagittal image). The central illustration represents a sagittal slice of the knee joint. The anterior femoral subregion (A) corresponds to the trochlea, a component of the patellofemoral joint. The central (C) and (P) posterior femoral subregions, as well as the anterior (A), central (C) and posterior (P) subregions of the tibia comprise the tibiofemoral joint. In the right illustration, which represents a coronal slice, the tibiofemoral joint is divided into the lateral (L) and medial (M) subregions. The tibia has a subspinous (S) subregion. In the present study, all but tibial S subregion was included for analysis. Osteoarthritis and Cartilage 2014 22, 76-83DOI: (10.1016/j.joca.2013.10.007) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Graphic representation of the semiquantitative grading of cartilage damage using the WORMS with actual examples of MRI. Cartilage signal and morphology were scored using an eight-point scale: 0 = normal and thickness and signal; 1 = normal thickness but increased signal on FS PD-weighted TSE image; 2.0 = partial-thickness focal defect <1 cm in greatest width; 2.5 = full-thickness focal defect <1 cm in greatest width; 3 = multiple areas of partial-thickness (grade 2.0) defects intermixed with areas of normal thickness, or a grade 2.0 defect wider than 1 cm but <75% of the subregion; 4 = diffuse (≥75% of the subregion) partial-thickness loss; 5 = multiple areas of full-thickness loss (grade 2.5) or a grade 2.5 lesion wider than 1 cm but <75% of the subregion; 6 = diffuse (≥75% of the subregion) full-thickness loss. Osteoarthritis and Cartilage 2014 22, 76-83DOI: (10.1016/j.joca.2013.10.007) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Example of an osteophyte that was not visible on radiography but was on MRI. (a) No obvious osteophyte is visualized at the margin of medial femur in this radiograph. The bony margin appears smooth (arrow). (b) Coronal intermediate-weighted fat-suppressed image clearly depicts a grade 4 osteophyte (arrow) at the margin of the medial distal femur. In (a), the osteophyte cannot be visualized because of overlapping normal bony margin of the distal femur. Osteoarthritis and Cartilage 2014 22, 76-83DOI: (10.1016/j.joca.2013.10.007) Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions