Masanobu Ishii et al. BTS 2017;2:

Slides:

Advertisements

Similar presentations

GnRH agonist and GnRH antagonist protocols in ovarian stimulation: differential regulation pathway of aromatase expression in human granulosa cells Mohamad.

Advertisements

Simvastatin modulates chemokine and chemokine receptor expression by geranylgeranyl isoprenoid pathway in human endothelial cells and macrophages Niels.

In vitro effect of caffeic acid phenethyl ester on matrix metalloproteinases (MMP-1 and MMP-9) and their inhibitor (TIMP-1) in lipopolysaccharide-activated.

a b c d Supplementary Figure 2 Bone marrow derived macrophage

Epigallocatechin-3-Gallate Inhibits Matrix Metalloproteinase-9 and Monocyte Chemotactic Protein-1 Expression Through the 67-κDa Laminin Receptor and the.

Volume 83, Issue 5, Pages (May 2013)

KG-501 suppresses NSCLC/IL-1β CM–induced migration of HUVECs by regulating IL-1β–induced CXC chemokine gene expression in NSCLC cells. KG-501 suppresses.

LPS-Induced Upregulation of SHIP Is Essential for Endotoxin Tolerance

IL-1β stimulates CXCL5 and CXCL8 gene expression and protein secretion in A549 cells in a time- and dose-dependent manner. IL-1β stimulates CXCL5 and CXCL8.

CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin-6 production by Giuseppe Sconocchia, Laura Campagnano, Domenico Adorno, Angela.

Ex vivo effects of proNGF and NGF on JIA mononuclear cells.

Differential Regulation by IL-1β and EGF of Expression of Three Different Hyaluronan Synthases in Oral Mucosal Epithelial Cells and Fibroblasts and Dermal.

M. -H. Moon, J. -K. Jeong, Y. -J. Lee, J. -W. Seol, C. J. Jackson, S

Masanobu Ishii et al. BTS 2017;2:

Inhibition of ILK by QLT-0267 abrogates PAI-1 and MMP-2 induction by TGF-β1 in tubular epithelial cells. Inhibition of ILK by QLT-0267 abrogates PAI-1.

Volume 25, Issue 6, Pages (December 2006)

Characterization of TNF-α– and IL-17A–Mediated Synergistic Induction of DEFB4 Gene Expression in Human Keratinocytes through IκBζ Claus Johansen, Trine.

NF-κBp65-specific siRNA inhibits expression of genes of COX-2, NOS-2 and MMP-9 in rat IL-1β-induced and TNF-α-induced chondrocytes Dr C. Lianxu, Ph.D.,

Volume 24, Issue 5, Pages (May 2006)

Charlotte Andersson, Munir M. Zaman, Amanda B. Jones, Steven D

Yiping Wang, Yuet-Ching Tay, David C.H. Harris Kidney International

Effect of moxifloxacin on secretion of cytokines by human monocytes stimulated with lipopolysaccharide F.G. Araujo, T.L. Slifer, J.S. Remington Clinical.

PDGFRα GBM primary cultures demonstrate titratable and temporal DOX-inducible expression of hPDGF-A and receptor activation. PDGFRα GBM primary cultures.

Maturation, Ag presentation capacity, and IL-12 production of DCs

Heloise Mongue-Din et al. BTS 2017;2:

Comparison of cytokine profiles induced by ChiLob 7/4 and TLR ligands in ex vivo whole-blood stimulation assays. Comparison of cytokine profiles induced.

Isoliquiritigenin Inhibits IL-1β-Induced Production of Matrix Metalloproteinase in Articular Chondrocytes Lei Zhang, Shiyun Ma, Hang Su, Jiaxiang Cheng

Volume 57, Issue 2, Pages (October 2000)

Regulation of renal proximal tubular epithelial cell hyaluronan generation: Implications for diabetic nephropathy Stuart Jones, Suzanne Jones, Aled Owain.

Defensin Is Suppressed by Tick Salivary Gland Extract During the In Vitro Interaction of Resident Skin Cells with Borrelia burgdorferi Claire M.P. Marchal,

Volume 22, Issue 3, Pages (March 2005)

Takashi Kobayashi, Hiroshi Shinkai

Volume 19, Issue 6, Pages (May 2017)

Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes

Izabella Z.A. Pawluczyk, Kevin P.G. Harris Kidney International

Kellie J. White, Vincent J. Maffei, Marvin Newton-West, Robert A

Macrophages uptake extracellular mitochondria from apoptotic cells, inducing caspase-1 activation and IL-1β production. Macrophages uptake extracellular.

CD137/NFATc1 Axis Activated NLRP3 Inflammasome in Vascular Smooth Muscle Cells (A) Western blot and quantitative results of NLRP3, pro-IL-1β, and mature.

Volume 8, Issue 5, Pages (May 1998)

Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes M.H. Stradner,

SIRT1, a Class III Histone Deacetylase, Regulates LPS-Induced Inflammation in Human Keratinocytes and Mediates the Anti-Inflammatory Effects of Hinokitiol

Volume 5, Issue 5, Pages (May 2009)

Th2 Cytokines Suppress Lipoteichoic Acid–Induced Matrix Metalloproteinase Expression and Keratinocyte Migration in Response to Wounding Anne M. Brauweiler,

Inflammatory cytokine secretion from THP-1 cells, luciferase reporter assay of Nod2-mediated NF-κB activation and NLRP3 expression. Inflammatory cytokine.

VEGF-A concentration is increased in vivo in response to DC101 and in vitro in response to FG VEGF-A concentration is increased in vivo in response.

Christopher T. Nguyen et al. BTS 2018;3:97-109

Volume 114, Issue 6, Pages (June 1998)

Volume 64, Issue 6, Pages (December 2003)

Volume 2, Issue 2, Pages (February 2008)

Volume 122, Issue 7, Pages (June 2002)

Blazej Zbytek, Andrzej T. Slominski

Laura Z. Vanags et al. BTS 2018;3:

Effect of YopM on the transcription of pro-inflammatory cytokines in HL60-derived macrophages after stimulation with LPS. HL60 cells differentiated into.

Figure 2 Glatiramer acetate treatment induced M2 differentiation through a MyD88-independent pathway (A) As described previously,3 M2 monocytes were treated.

Figure 3 Fingolimod inhibits TNF-α secretion by human monocytes Peripheral blood mononuclear cells from healthy donors were briefly exposed to increasing.

Lower SNS activity in WAT of fasted Ugcgf/f//CamKCreERT2 mice.

Oxalate stimulates IL-6 production in HK-2 cells, a line of human renal proximal tubular epithelial cells M.E.I. Y.I. Huang, Lakshmi S. Chaturvedi, Sweaty.

Molecular Therapy - Methods & Clinical Development

DPP-4 enhances M1 polarization and inhibits M2 polarization in macrophages in an ROS-dependent manner. DPP-4 enhances M1 polarization and inhibits M2 polarization.

A. baumannii stimulates the autophagy.

Figure 2 LMNB1 mRNA expression

Upregulation of TRPM2 and production of CXCL2 in cultured macrophages that evoked mechanical allodynia after intraplantar injection. Upregulation of TRPM2.

BORIS mRNA expression in DNMT deficient HCT116 cell lines.

Hybridomas expressing Vγ1. 1Vδ6

Secretion of TNF-α from macrophages and monocytic cells were reduced by the deletion of Nrdc. Secretion of TNF-α from macrophages and monocytic cells were.

T cell effector cytokines and staphylococcal products regulate CCL18.

Volume 19, Issue 6, Pages (May 2017)

Volume 27, Issue 5, Pages (May 2019)

Analysis of TNF-α gene transcription and mRNA accumulation in THP-1 cells. Analysis of TNF-α gene transcription and mRNA accumulation in THP-1 cells. (A)

Presentation transcript:

Masanobu Ishii et al. BTS 2017;2:655-668 Combined Effects of Valsartan With LBQ657 in In Vitro Assay Using Peritoneal Macrophages (A) Gelatin zymography on the supernatants of peritoneal macrophages stimulated with LPS (10 ng/ml) for 48 h. (B) Semi-quantitative analysis of gelatinolytic activity showed significantly lower activity in VAL + LBQ compared to the VAL-alone and LBQ-alone groups. n = 6 per group. Quantification of (C) IL-1β, and (D) IL-6 concentrations in the supernatants of peritoneal macrophages stimulated with LPS (10 ng/ml) for 48 h. n = 6 per group. (E to G) Real-time reverse transcriptase PCR result for (E) MMP-9, (F) IL-1β, and (G) IL-6 mRNA level in peritoneal macrophages stimulated with LPS (10 ng/ml) for 48 h. The mRNA level was normalized by the level of endogenous control beta-2-microglobulin RNA. n = 8 per group. Results were mean ± SD. Ctrl = control; LBQ = LBQ657; LPS = lipopolysaccharide; VAL = valsartan; other abbreviations as in Figure 4. Masanobu Ishii et al. BTS 2017;2:655-668 2017 The Authors