No evidence of association between blastocyst aneuploidy and morphokinetic assessment in a selected population of poor-prognosis patients: a longitudinal.

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No evidence of association between blastocyst aneuploidy and morphokinetic assessment in a selected population of poor-prognosis patients: a longitudinal cohort study L. Rienzi, A. Capalbo, M. Stoppa, S. Romano, R. Maggiulli, L. Albricci, C. Scarica, A. Farcomeni, G. Vajta, F.M. Ubaldi Reproductive BioMedicine Online Volume 30, Issue 1, Pages 57-66 (January 2015) DOI: 10.1016/j.rbmo.2014.09.012 Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Time-lapse imaging of a forming blastocyst. (A) begining of the compaction process; (B) begining of the blastulation process; and (C) formation of the full blastocyst and begining of the expansion process (<10% diameter increase). Grading performed according to Campbell et al. (2013a). Reproductive BioMedicine Online 2015 30, 57-66DOI: (10.1016/j.rbmo.2014.09.012) Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 Distribution of euploid (green dots) and aneuploid (blue dots) embryos according to time (h) between intracytoplasmic sperm injection and completed versus initiated blastulation as suggested by Campbell et al. (2013a). Reproductive BioMedicine Online 2015 30, 57-66DOI: (10.1016/j.rbmo.2014.09.012) Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions

Figure 3 Percentage of euploid embryos according to hierarchical classification as suggested by Basile et al. (2014). The embryo is categorized as A or B if the value of completion of interval for completion of cleavage from to two to five cells is more than 20.5 h; on the other hand, if the value is outside this range, the embryo is categorized as C or D. Moreover, if the value of the third cell cycle fell inside the range 11.7–18.2 h, the embryo is categorized as A or C depending on completion of interval for completion of cleavage from to two to five cells; if the value of the third cell cycle fell outside the range, the embryo was categorized as B or D depending on completion of interval for completion of cleavage from to two to five cells. Reproductive BioMedicine Online 2015 30, 57-66DOI: (10.1016/j.rbmo.2014.09.012) Copyright © 2014 Reproductive Healthcare Ltd. Terms and Conditions