Hypertension promotes integrin expression and reactive oxygen species generation by circulating leukocytes Choong H. Kim, Nosratola D. Vaziri Kidney.

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Hypertension promotes integrin expression and reactive oxygen species generation by circulating leukocytes Choong H. Kim, Nosratola D. Vaziri Kidney International Volume 67, Issue 4, Pages 1462-1470 (April 2005) DOI: 10.1111/j.1523-1755.2005.00223.x Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 1 Representative overlay histograms and group data depicting superoxide production by CD4+ and CD8+ T lymphocytes and granulocytes in the blood of rats with abdominal aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line). N = 5 in each group, *P < 0.05. #D value greater than 0.2 denotes statistical significance. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 2 Representative overlay histograms and group data depicting superoxide production by CD4+ and CD8+ T lymphocytes in the spleen of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line).N = 5 in each group. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 3 Representative overlay histograms and group data depicting hydrogen peroxide production by CD4+ and CD8+ T lymphocytes and granulocytes in the blood of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line).N = 5 in each group, *P < 0.05. #D value greater than 0.2 denotes statistical significance. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 4 Representative overlay histograms and group data depicting hydrogen peroxide production by CD4+ and CD8 + T lymphocytes in the spleen of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line).N = 5 in each group, *P < 0.05. #D value greater than 0.2 denotes statistical significance. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 5 Expression of integrin (CD11a, CD11b, CD18) and IL-2 receptor (CD25) in CD4+ and CD8 + T lymphocytes and granulocytes in the blood of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line). #D value greater than 0.2 denotes statistical significance. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 6 Expression of integrin (CD11a, CD11b, CD18) and IL-2 receptor (CD25) in CD4+ and CD8+ T lymphocytes in the spleen of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line). #D value greater than 0.2 denotes statistical significance. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 7 Representative overlay histograms and group data depicting cytosolic Ca2+ in the basal and activated peripheral blood and splenic mononuclear cells of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line). N = 6, *P < 0.05. #D value greater than 0.2 denotes statistical significance. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions

Figure 8 Blood pressure and peripheral blood leukocyte counts of rats with aorta banding-induced hypertension (heavy line), and the sham-operated control rats (thin line). N = 5, *P < 0.001. Kidney International 2005 67, 1462-1470DOI: (10.1111/j.1523-1755.2005.00223.x) Copyright © 2005 International Society of Nephrology Terms and Conditions