Volume 375, Issue 9728, Pages (May 2010)

Slides:

Advertisements

Similar presentations

Crohn's disease Prof Daniel C Baumgart, MD, Prof William J Sandborn, MD The Lancet Volume 380, Issue 9853, Pages (November 2012) DOI: /S (12)

Advertisements

Towards universal access to HIV prevention, treatment, care, and support: the role of tuberculosis/HIV collaboration Alasdair Reid, MD, Fabio Scano,

Routine invasive management early after fibrinolysis: Relationship between baseline risk and treatment effects in a pooled patient-level analysis of 7.

Volume 6, Issue 7, Pages (July 2005)

Volume 357, Issue 9257, Pages (March 2001)

Volume 355, Issue 9221, Pages (June 2000)

Pharmacogenetics and future drug development and delivery

Volume 376, Issue 9747, Pages (October 2010)

Urine antigen test for diagnosis of HIV-associated tuberculosis

Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV- associated pulmonary tuberculosis before antiretroviral therapy:

Volume 3, Issue 3, Pages (March 2016)

Volume 380, Issue 9845, Pages (September 2012)

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa? Dr Simone Lanini, MD, Prof Alimuddin.

Volume 386, Issue 9992, Pages (August 2015)

Diagnostic accuracy of a low-cost, urine antigen, point-of-care screening assay for HIV- associated pulmonary tuberculosis before antiretroviral therapy:

Volume 2, Issue 4, Pages e151-e158 (April 2015)

Volume 11, Issue 6, Pages (June 2012)

Yield of HIV-associated tuberculosis during intensified case finding in resource-limited settings: a systematic review and meta-analysis Katharina Kranzer,

Paediatric HIV-1 infection

Volume 5, Issue 4, Pages (April 2006)

Volume 377, Issue 9783, Pages (June 2011)

Transmission of Staphylococcus aureus between health-care workers, the environment, and patients in an intensive care unit: a longitudinal cohort study.

Volume 13, Issue 12, Pages (December 2012)

Evaluation of early administration of simvastatin in the prevention and treatment of delirium in critically ill patients undergoing mechanical ventilation.

Outcomes, infectiousness, and transmission dynamics of patients with extensively drug- resistant tuberculosis and home-discharged patients with programmatically.

Volume 13, Issue 3, Pages (March 2012)

Volume 9, Issue 12, Pages (December 2010)

Volume 2, Issue 12, Pages e530-e539 (December 2015)

Characteristics and survival of patients with Ebola virus infection, malaria, or both in Sierra Leone: a retrospective cohort study Matthew Waxman, MD,

Volume 379, Issue 9811, Pages (January 2012)

Volume 371, Issue 9624, Pages (May 2008)

WHO's new guidelines for antiretroviral treatment

Accuracy of the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in children admitted to hospital in Cape Town, South Africa: a descriptive.

Trends in virological and clinical outcomes in individuals with HIV-1 infection and virological failure of drugs from three antiretroviral drug classes:

Risk stratification after paracetamol overdose using mechanistic biomarkers: results from two prospective cohort studies James W Dear, FRCP, Joanna I.

Volume 2, Issue 6, Pages (June 2015)

Mortality and causes of death in people diagnosed with HIV in the era of highly active antiretroviral therapy compared with the general population: an.

Socioeconomic differences in mortality in the antiretroviral therapy era in Agincourt, rural South Africa, 2001–13: a population surveillance analysis

Volume 379, Issue 9814, Pages (February 2012)

Are adaptive randomised trials or non-randomised studies the best way to address the Ebola outbreak in west Africa? Dr Simone Lanini, MD, Prof Alimuddin.

Volume 378, Issue 9800, Pages (October 2011)

Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: a systematic review and meta-analysis Ulla Beijer, PhD, Achim Wolf, MSc, Dr.

Resuscitation at birth and cognition at 8 years of age: a cohort study

Volume 379, Issue 9812, Pages (January 2012)

Volume 356, Issue 9241, Pages (November 2000)

Volume 380, Issue 9849, Pages (October 2012)

Socioeconomic differences in mortality in the antiretroviral therapy era in Agincourt, rural South Africa, 2001–13: a population surveillance analysis

Volume 13, Issue 12, Pages (December 2012)

Volume 380, Issue 9845, Pages (September 2012)

Volume 11, Issue 3, Pages (March 2012)

Volume 386, Issue 9992, Pages (August 2015)

Volume 381, Issue 9868, Pages (March 2013)

Pre-entry screening programmes for tuberculosis in migrants to low-incidence countries: a systematic review and meta-analysis Dr Robert W Aldridge, MSc,

Volume 379, Issue 9812, Pages (January 2012)

Volume 392, Issue 10144, Pages (July 2018)

Volume 2, Issue 6, Pages e243-e251 (June 2015)

Volume 371, Issue 9627, Pages (May 2008)

Volume 378, Issue 9786, Pages (July 2011)

Volume 2, Issue 10, Pages e417-e426 (October 2015)

Urine antigen test for diagnosis of HIV-associated tuberculosis

Volume 372, Issue 9634, Pages (July 2008)

Prof GJB van Ommen, PhD, E Bakker, PhD, JT den Dunnen, PhD The Lancet

Volume 15, Issue 8, Pages (July 2014)

Volume 375, Issue 9722, Pages (April 2010)

ACST: which subgroups will benefit most from carotid endarterectomy?

Volume 376, Issue 9734, Pages (July 2010)

Volume 381, Issue 9878, Pages (May 2013)

Volume 373, Issue 9672, Pages (April 2009)

Costs of eliminating HIV in South Africa have been underestimated

Volume 376, Issue 9747, Pages (October 2010)

Presentation transcript:

Volume 375, Issue 9728, Pages 1798-1807 (May 2010) Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study Dr Keertan Dheda, PhD, Karen Shean, MSc, Prof Alimuddin Zumla, FRCP, Motasim Badri, PhD, Elizabeth M Streicher, PhD, Liesl Page- Shipp, MBBCh, Paul Willcox, FCP, Melanie-Anne John, FCPath, Gary Reubenson, FCP, Darshini Govindasamy, BSc, Prof Michelle Wong, PhD, Xavier Padanilam, MCFP, Alicia Dziwiecki, MD, Prof Paul D van Helden, PhD, Sweetness Siwendu, MBChB, Julie Jarand, MD, Colin N Menezes, FCP, Avril Burns, BA, Prof Thomas Victor, PhD, Prof Robin Warren, PhD, Prof Martin P Grobusch, PhD, Martie van der Walt, PhD, Charlotte Kvasnovsky, BSc The Lancet Volume 375, Issue 9728, Pages 1798-1807 (May 2010) DOI: 10.1016/S0140-6736(10)60492-8 Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 1 Study profile (A), and timeline for data gathering stratified by recruitment institution (B) MDR=multidrug-resistant. XDR=extensively drug-resistant. *Local approval was only obtained for this period. The Lancet 2010 375, 1798-1807DOI: (10.1016/S0140-6736(10)60492-8) Copyright © 2010 Elsevier Ltd Terms and Conditions

Figure 2 Kaplan-Meier estimates of culture-conversion and deaths in patients with extensively drug-resistant tuberculosis (A) Probabilities of culture conversion in patients with and without HIV infection given treatment; (B) probabilities of death in patients who died before initiation of treatment stratified by HIV status; (C) probabilities of death in patients with and without HIV infection given treatment from date of treatment initiation; and (D) probabilities of death in patients with HIV infection given treatment stratified according to use of highly active antiretroviral therapy. The Lancet 2010 375, 1798-1807DOI: (10.1016/S0140-6736(10)60492-8) Copyright © 2010 Elsevier Ltd Terms and Conditions