Results of PREVENT III: A multicenter, randomized trial of edifoligide for the prevention of vein graft failure in lower extremity bypass surgery Michael.

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Presentation transcript:

Results of PREVENT III: A multicenter, randomized trial of edifoligide for the prevention of vein graft failure in lower extremity bypass surgery Michael S. Conte, MD, Dennis F. Bandyk, MD, Alexander W. Clowes, MD, Gregory L. Moneta, MD, Lynn Seely, MD, Todd J. Lorenz, MD, Hamid Namini, PhD, Allen D. Hamdan, MD, Sean P. Roddy, MD, Michael Belkin, MD, Scott A. Berceli, MD, Richard J. DeMasi, MD, Russell H. Samson, MD, Scott S. Berman, MD Journal of Vascular Surgery Volume 43, Issue 4, Pages 742-751.e1 (April 2006) DOI: 10.1016/j.jvs.2005.12.058 Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 1 Analysis of protocol-specified end points by the Kaplan-Meier method (P = not significant for all). A, Primary study end point: nontechnical index graft failure. B, All-cause index graft failure. C, Freedom from clinically significant index graft stenosis. D, Event-free survival. Journal of Vascular Surgery 2006 43, 742-751.e1DOI: (10.1016/j.jvs.2005.12.058) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions

Fig 2 Outcomes at 1 year by the Kaplan-Meier method. A, Primary graft patency (P = not significant). B, Primary assisted graft patency (P = not significant). C, Secondary graft patency (P = .016; log-rank test). D, Limb salvage (P = not significant). E, Patient survival (P = not significant). Journal of Vascular Surgery 2006 43, 742-751.e1DOI: (10.1016/j.jvs.2005.12.058) Copyright © 2006 The Society for Vascular Surgery Terms and Conditions