Joint space narrowing and Kellgren–Lawrence progression in knee osteoarthritis: an analytic literature synthesis P.S. Emrani, B.S., J.N. Katz, M.D.,

Slides:

Advertisements

Similar presentations

The relationship between specific tissue lesions and pain severity in persons with knee osteoarthritis Ms L. Torres, B.A., Dr D.D. Dunlop, Ph.D., Dr C.

Advertisements

The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy P.T. Paradowski, L.S. Lohmander,

Knee osteoarthritis radiographic progression and associations with pain and function prior to knee arthroplasty: a multicenter comparative cohort study

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

D. Pereira, B. Peleteiro, J. Araújo, J. Branco, R.A. Santos, E. Ramos

Understanding the pain experience in hip and knee osteoarthritis – an OARSI/OMERACT initiative G.A. Hawker, M.D., M.Sc., L. Stewart, M.Sc., M.R. French,

Association of knee and ankle osteoarthritis with physical performance

P.T. Paradowski, L.S. Lohmander, M. Englund

A systematic review of the association between radiographic and clinical osteoarthritis of hip and knee M.B. Kinds, P.M.J. Welsing, E.P. Vignon, J.W.J.

L. Kalichman, Ph. D. , P. T. , I. Malkin, Ph. D. , M. J. Seibel, Ph. D

Impact of a daily exercise dose on knee joint cartilage – a systematic review and meta- analysis of randomized controlled trials in healthy animals A.

The epidemiology and impact of pain in osteoarthritis

Validity and sensitivity to change of three scales for the radiographic assessment of knee osteoarthritis using images from the Multicenter Osteoarthritis.

Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort W. Wirth, M.S., M.-P. Hellio.

P.-S. Hsu, H.-H. Lin, C.-R. Li, W.-S. Chung

Associations between pre-operative radiographic changes and outcomes after total knee joint replacement for osteoarthritis M.M. Dowsey, M. Nikpour, P.

Synovial changes detected by ultrasound in people with knee osteoarthritis – a meta- analysis of observational studies A. Sarmanova, M. Hall, J. Moses,

P.T. Paradowski, L.S. Lohmander, M. Englund

Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment – data.

Lifetime body mass index, other anthropometric measures of obesity and risk of knee or hip osteoarthritis in the GOAL case-control study K.L. Holliday,

C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study G. Engström, M.D., Ph.D.,

Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: the ROAD study T. Iidaka, S. Muraki, T. Akune,

D. Kumar, K.T. Manal, K.S. Rudolph Osteoarthritis and Cartilage

Characterization of pro-apoptotic and matrix-degradative gene expression following induction of osteoarthritis in mature and aged rabbits Dr. C.M. Robertson,

Time to be positive about negative data?

Association of radiographic and symptomatic knee osteoarthritis with health-related quality of life in a population-based cohort study in Japan: the ROAD.

Are bisphosphonates efficacious in knee osteoarthritis

OA phenotypes, rather than disease stage, drive structural progression – identification of structural progressors from 2 phase III randomized clinical.

E. Losina, S. A. Burbine, L. G. Suter, D. J. Hunter, D. H. Solomon, M

Evaluations of radiographic joint space – do they adequately predict cartilage conditions in the patellofemoral joint of the patients undergoing total.

Knee Images Digital Analysis (KIDA): a novel method to quantify individual radiographic features of knee osteoarthritis in detail A.C.A. Marijnissen,

Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees – data.

A double-blind randomized controlled trial comparing alternate forms of high molecular weight hyaluronan for the treatment of osteoarthritis of the knee

Feasibility of bone density evaluation using plain digital radiography

Serum cartilage oligomeric matrix protein (sCOMP) is elevated in patients with knee osteoarthritis: a systematic review and meta-analysis J.M. Hoch,

Is long-term physical activity safe for older adults with knee pain

Natural history of cartilage damage and osteoarthritis progression on magnetic resonance imaging in a population-based cohort with knee pain J. Cibere,

Assessment of joint space narrowing with conventional standing antero-posterior radiographs: relief in mild-to-moderate pain is not a confounder in recent.

Osteoarthritis of the knee after meniscal resection: long term radiographic evaluation of disease progression P.T. Paradowski, L.S. Lohmander, M. Englund

M.Y. Chan, J.R. Center, J.A. Eisman, T.V. Nguyen

Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis M. Blagojevic, C. Jinks, A. Jeffery, K.P.

Association between statin use and consultation or surgery for osteoarthritis of the hip or knee: a pooled analysis of four cohort studies K. Michaëlsson,

Who should have a joint replacement? A plea for more ‘phronesis’

Knee Injury and Osteoarthritis Outcome Score (KOOS): systematic review and meta- analysis of measurement properties N.J. Collins, C.A.C. Prinsen, R. Christensen,

Progression of cartilage damage and meniscal pathology over 30 months is associated with an increase in radiographic tibiofemoral joint space narrowing.

Natural history of pain and disability among African–Americans and Whites with or at risk for knee osteoarthritis: A longitudinal study E.R. Vina, D.

Trajectories and risk profiles of pain in persons with radiographic, symptomatic knee osteoarthritis: data from the osteoarthritis initiative J.E. Collins,

X. Li, Ph. D. , C. Benjamin Ma, M. D. , T. M. Link, M. D. , D. -D

G. H. Lo, M. D. , M. Sc. , J. Niu, M. D. , D. Sc. , C. E. McLennan, M

D.J. Hunter Osteoarthritis and Cartilage

The risk of osteoarthritis progression after arthroscopic partial meniscectomy (APM); data from an rct of APM vs. physical therapy J.E. Collins, E. Losina,

A comparison of intra-articular hyaluronan injection accuracy rates between three approaches based on radiographic severity of knee osteoarthritis Y.

S. Kobayashi, E. Pappas, M. Fransen, K. Refshauge, M. Simic

S.G. Muthuri, D.F. McWilliams, M. Doherty, W. Zhang

Therapeutic trajectory following intra-articular hyaluronic acid injection in knee osteoarthritis – meta-analysis R.R. Bannuru, N.S. Natov, U.R. Dasi,

Body mass index and alignment and their interaction as risk factors for progression of knees with radiographic signs of osteoarthritis E. Yusuf, J. Bijsterbosch,

Electromyographic patterns suggest changes in motor unit physiology associated with early osteoarthritis of the knee S.M. Ling, M.D., R.A. Conwit, M.D.,

Acute resistance exercise and pressure pain sensitivity in knee osteoarthritis: a randomised crossover trial N.J. Burrows, J. Booth, D.L. Sturnieks,

Development and preliminary evaluation of the OsteoArthritis Questionnaire (OA- Quest): a psychometric study L. Busija, R. Buchbinder, R.H. Osborne Osteoarthritis.

Osteoarthritis year 2012 in review: biology

Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis J.M. Jordan, M.F. Sowers, S.P. Messier, J. Bradley, G. Arangio,

Location-specific hip joint space width for progression of hip osteoarthritis – Data from the Osteoarthritis Initiative C. Ratzlaff, C. Van Wyngaarden,

D.T. Felson Osteoarthritis and Cartilage

Prevalence of radiographic knee osteoarthritis and its association with knee pain in the elderly of Japanese population-based cohorts: The ROAD study

Is the atrophic phenotype of tibiofemoral osteoarthritis associated with faster progression of disease? The MOST study M.D. Crema, D.T. Felson, A. Guermazi,

The relationship between foot and ankle symptoms and risk of developing knee osteoarthritis: data from the osteoarthritis initiative K.L. Paterson, J.

D.F. McWilliams, B.F. Leeb, S.G. Muthuri, M. Doherty, W. Zhang

Changes in pain, stiffness and physical function in patients with osteoarthritis waiting for hip or knee joint replacement surgery H. Kapstad, R.N.,

Symptomatic efficacy of avocado–soybean unsaponifiables (ASU) in osteoarthritis (OA) patients: a meta-analysis of randomized controlled trials R. Christensen,

Measurement of synovial fluid volume using urea

Presentation transcript:

Joint space narrowing and Kellgren–Lawrence progression in knee osteoarthritis: an analytic literature synthesis P.S. Emrani, B.S., J.N. Katz, M.D., M.S., C.L. Kessler, B.A., W.M. Reichmann, M.A., E.A. Wright, Ph.D., T.E. McAlindon, M.D., M.P.H., Chief, E. Losina, Ph.D. Osteoarthritis and Cartilage Volume 16, Issue 8, Pages 873-882 (August 2008) DOI: 10.1016/j.joca.2007.12.004 Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 1 Manuscript search and selection process. Osteoarthritis and Cartilage 2008 16, 873-882DOI: (10.1016/j.joca.2007.12.004) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 2 Annual JSN stratified by study design and radiographic approach. Circles represent individual mean JSN estimates. Circle area is proportional to sample size of corresponding cohort. Means within study design and radiographic approach sub-categories are depicted in gray. Overall means within each study design category and the overall mean for all estimates are depicted in black. The means are displayed above corresponding circles, with error bars representing 95% CIs. Each study reference is denoted next the circle, representing the corresponding manuscript from which the progression estimate was derived. An estimate of 0.7mm/year29 (RCT, full extension) is not shown for scaling purposes. Osteoarthritis and Cartilage 2008 16, 873-882DOI: (10.1016/j.joca.2007.12.004) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 3 Annual risk of K–L progression stratified by cohort composition. Circles represent individual estimates of the proportion of the cohort that progressed by at least one K–L grade per year of follow-up time. Circle area is proportional to sample size of corresponding cohort. Means within each cohort composition category are depicted in gray. Overall mean for all reviewed K–L studies is depicted in black. The means are displayed above corresponding circles, with error bars representing 95% CIs. Each study reference is denoted next the circle, representing the corresponding manuscript from which the progression estimate was derived. Osteoarthritis and Cartilage 2008 16, 873-882DOI: (10.1016/j.joca.2007.12.004) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions

Fig. 4 Association of OA progression [JSN (A) and K–L (B)] and study duration. Circles represent individual estimates of the proportion of the cohort that progressed by at least one K–L grade per year of follow-up time. Circle area is proportional to sample size of corresponding cohort. Regression line for follow-up time is weighted for sample size and adjusted for radiographic approach (A and B), OA definition (B), and cohort composition (B). Osteoarthritis and Cartilage 2008 16, 873-882DOI: (10.1016/j.joca.2007.12.004) Copyright © 2007 Osteoarthritis Research Society International Terms and Conditions