Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Classification.

Slides:

Advertisements

Similar presentations

OCT= Optical Coherence Tomography

Advertisements

Copyright restrictions may apply JAMA Ophthalmology Journal Club Slides: Retinal Nerve Fiber Layer Loss and Quality of Life in Glaucoma Gracitelli CPB,

Patient Preferences in the Treatment of Neovascular Age-Related Macular Degeneration Sabrina Mueller, MSc, Hansjürgen Agostini, MD, Christoph Ehlken, MD,

Low-Dose Aspirin in Patients with Stable Cardiovascular Disease: A Meta-analysis Jeffrey S. Berger, MD, MS, David L. Brown, MD, Richard C. Becker, MD The.

1. Ankara University School of Medicine, Department of Ophthalmology

and Microperimetry visual field parameters for Glaucomatous Loss

Volume 123, Issue 6, Pages (June 2016)

Iwona Helemejko, MD 1; D. Robert Iskander, PhD2

Foveal Hypoplasia in Patients with Stickler Syndrome

Aflibercept, Bevacizumab, or Ranibizumab for Diabetic Macular Edema

Volume 113, Issue 7, Pages 1187.e e12 (July 2006)

Volume 123, Issue 3, Pages (March 2016)

Microcystic Macular Edema

Correlation between Optical Coherence Tomography and Fluorescein Angiography Findings in Diabetic Macular Edema Tomohiro Otani, MD, Shoji Kishi, MD

Analysis of Macular Edema after Cataract Surgery in Patients with Diabetes Using Optical Coherence Tomography Stephen J. Kim, MD, Robert Equi, MD, Neil.

Correlation between Deep Capillary Plexus Perfusion and Long-Term Photoreceptor Recovery after Diabetic Macular Edema Treatment Byung Gil Moon, MD, Taewoong.

From: Clustering of Combined 24-2 and 10-2 Visual Field Grids and Their Relationship With Circumpapillary Retinal Nerve Fiber Layer Thickness Invest. Ophthalmol.

P-WT-294 Comparison of red-free photography, swept-source OCT and spectral-domain OCT for evaluation of retinal nerve fiber layer defects. Gilda WK Lai,

Asymmetry Analysis of Retinal Thickness

Volume 122, Issue 3, Pages (March 2015)

Volume 123, Issue 6, Pages (June 2016)

Nabil El Ayoubi MD, Helen Sawaya, MSc., Raja Sawaya MD.

Volume 123, Issue 10, Pages (October 2016)

Structure-Function Relationship Between the Bruch Membrane Opening-based Minimum Rim Width and Visual Field Defects in Advanced Glaucoma Serhat Imamoglu,

From: Relationship Between Optic Nerve Appearance and Retinal Nerve Fiber Layer Thickness as Explored with Spectral Domain Optical Coherence Tomography.

From: Central Glaucomatous Damage of the Macula Can Be Overlooked by Conventional OCT Retinal Nerve Fiber Layer Thickness Analyses Trans. Vis. Sci. Tech..

From: Relating Retinal Ganglion Cell Function and Retinal Nerve Fiber Layer (RNFL) Retardance to Progressive Loss of RNFL Thickness and Optic Nerve Axons.

American Journal of Ophthalmology

Volume 114, Issue 3, Pages (March 2007)

Quantitative analysis of retinal OCT

Volume 122, Issue 7, Pages (July 2015)

David B Henson Medical School University of Manchester

Transscleral Diode Laser Cyclophotocoagulation

Glaucoma Diagnosis Ophthalmology Glaucoma

Figure 2 ERG amplitude reduction in the follow-up study

Mitral stenosis with pulmonary hypertension: We should operate early

Differences in Performance Status Assessment Among Palliative Care Specialists, Nurses, and Medical Oncologists Yu Jung Kim, MD, PhD, David Hui, MD,

Prospective Randomized Trial Comparing Mitomycin C Combined with Ologen Implant versus Mitomycin C Alone as Adjuvants in Trabeculectomy Mrittika Sen,

John R. Meuleman, MD, William F. Brechue, PhD, Paul S

Association between Rates of Retinal Nerve Fiber Layer Thinning and Previous Disc Hemorrhage in Glaucoma Tadamichi Akagi, MD, Luke J. Saunders, PhD,

Comparison between Lamina Cribrosa Depth and Curvature as a Predictor of Progressive Retinal Nerve Fiber Layer Thinning in Primary Open-Angle Glaucoma

Distribution and Rates of Visual Field Loss across Different Disease Stages in Primary Open-Angle Glaucoma Siamak Yousefi, PhD, Golnoush Sadat Mahmoudi.

Mohamed S. Sayed, MD, Michael Margolis, MD, Jessica L

Effectiveness of Continued Ranibizumab Therapy in Neovascular Age-Related Macular Degeneration versus Switch to Aflibercept: Real World Evidence Usha.

Appendectomy is followed by increased risk of Crohn's disease

Figure 2 Optical coherence tomography of the human retina A) Detailed retinal segmentation sample on spectral-domain optical coherence tomography (OCT)

Position of Central Retinal Vascular Trunk and Preferential Location of Glaucomatous Damage in Myopic Normal-Tension Glaucoma Kyoung Min Lee, MD, Martha.

Optic neuritis: A mechanistic view

J. Alexander Torres, BS, Nathan A. Fischer, BS, Leonard K

Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up Hamed Esfandiari, MD,

Aaron Z. Priluck, BSE, Jamie Dietze, BS Ophthalmology Glaucoma

Sarah H. Van Tassel, MD, Sanjay G. Asrani, MD Ophthalmology Glaucoma

Figure 1 Example OCT scan

Figure 1 ERG peak time delay at baseline

The Relationship between the Waveform Parameters from the Ocular Response Analyzer and the Progression of Glaucoma Shuichiro Aoki, MD, Hiroshi Murata,

Erin G. Sieck, MD, Rebecca S. Epstein, MD, Jeffrey B

Atsuya Miki, MD, PhD, Yasushi Ikuno, MD, Robert N

Relationship between the Vertical Asymmetry of the Posterior Pole of the Eye and the Visual Field Damage in Glaucomatous Eyes Kazunori Hirasawa, CO,

Improving the Feasibility of Glaucoma Clinical Trials Using Trend-Based Visual Field Progression End Points Zhichao Wu, BAppSc(Optom), PhD, David P.

Figure 3 Critical flicker frequency measurements and visual function in MS Critical flicker frequency measurements and visual function in MS Association.

Correlation between Intraocular Pressure and Angle Configuration Measured by OCT Benjamin Y. Xu, MD, PhD, Bruce Burkemper, PhD, Juan Pablo Lewinger, PhD,

Figure 3 Local intraclass correlation coefficients

M. Alan Brookhart, PhD, Jerry Avorn, MD, Jeffrey N

Standalone Ab Interno Gelatin Stent versus Trabeculectomy

Development of a Novel Corneal Concavity Shape Parameter and Its Association with Glaucomatous Visual Field Progression Shuichiro Aoki, MD, Hiroshi Murata,

Factors Affecting Adherence to Topical Glaucoma Therapy

Multidrug-Resistant Organisms Within the Dialysis Population: A Potentially Preventable Perfect Storm David P. Calfee, MD, MS American Journal of Kidney.

Medicaid acceptance among pediatric dermatologists

Micropulse Transscleral Cyclophotocoagulation

Impact of Tumor Size on Local Control and Pneumonitis After Stereotactic Body Radiation Therapy for Lung Tumors Sean M. Parker, BS, R. Alfredo Siochi,

Presentation transcript:

Detecting Glaucoma Progression Using Guided Progression Analysis with OCT and Visual Field Assessment in Eyes Classified by International Classification of Disease Severity Codes Alexander T. Nguyen, MD, David S. Greenfield, MD, Amitabha S. Bhakta, PhD, Jennifer Lee, MD, William J. Feuer, MS Ophthalmology Glaucoma Volume 2, Issue 1, Pages 36-46 (January 2019) DOI: 10.1016/j.ogla.2018.11.004 Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 1 Histogram illustrating a comparison of glaucoma progression events identified using OCT retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) analysis and visual field (VF) testing in eyes with mild (n = 62), moderate (n = 39), and severe (n = 46) glaucoma. Ophthalmology Glaucoma 2019 2, 36-46DOI: (10.1016/j.ogla.2018.11.004) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 2 Venn diagram showing glaucoma progression detection using OCT retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) analysis and visual field (VF) testing among the study population (n = 147). Ophthalmology Glaucoma 2019 2, 36-46DOI: (10.1016/j.ogla.2018.11.004) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 3 OCT Guided Progression Analysis (GPA) of retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) thickness and visual field (VF) testing of the left eye of a patient with severe glaucoma illustrating glaucoma progression. On the right is a panomap consisting of combined RNFL and macular GCIPL deviation maps obtained at the baseline and final visit. The asterisks identify locations of progression highlighted on the spectral-domain OCT GPA images. PD = pattern deviation. Ophthalmology Glaucoma 2019 2, 36-46DOI: (10.1016/j.ogla.2018.11.004) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 4 Scatterplots demonstrating the relationship between the rate of visual field mean deviation (MD) loss and (A) OCT retinal nerve fiber layer (RNFL) loss in eyes with RNFL progression and (B) the rate of OCT ganglion cell–inner plexiform layer (GCIPL) loss in eyes with GCIPL progression. Ophthalmology Glaucoma 2019 2, 36-46DOI: (10.1016/j.ogla.2018.11.004) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions

Figure 5 Kaplan-Meier plot presenting the cumulative progression rates detected by OCT retinal nerve fiber layer (RNFL) and ganglion cell–inner plexiform layer (GCIPL) analysis and visual field (VF) testing in all eyes of all patients (n = 147). OCT detected significantly more progression events than VF testing (P < 0.001, McNemar’s test). Ophthalmology Glaucoma 2019 2, 36-46DOI: (10.1016/j.ogla.2018.11.004) Copyright © 2018 American Academy of Ophthalmology Terms and Conditions