Hippo: Hungry, Hungry for Melanoma Invasion Ileine M. Sanchez, Andrew E. Aplin  Journal of Investigative Dermatology  Volume 134, Issue 1, Pages 14-16 (January 2014) DOI: 10.1038/jid.2013.372 Copyright © 2014 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 The Hippo pathway signaling cascade results in the phosphorylation and cytoplasmic retention of effector molecules YAP and TAZ. Unphosphorylated YAP and TAZ can translocate to the nucleus to interact with TEAD transcription factors and regulate transcriptional events that promote melanoma invasion and metastasis. Journal of Investigative Dermatology 2014 134, 14-16DOI: (10.1038/jid.2013.372) Copyright © 2014 The Society for Investigative Dermatology, Inc Terms and Conditions

Journal of Investigative Dermatology 2014 134, 14-16DOI: (10. 1038/jid Copyright © 2014 The Society for Investigative Dermatology, Inc Terms and Conditions