Volume 120, Issue 1, Pages 170-178 (January 2001) Factors associated with poor health-related quality of life of patients with cirrhosis  Giulio Marchesini, Giampaolo Bianchi, Piero Amodio, Francesco Salerno, Manuela Merli, Carmine Panella, Carmela Loguercio, Giovanni Apolone, Mauro Niero, Roberto Abbiati  Gastroenterology  Volume 120, Issue 1, Pages 170-178 (January 2001) DOI: 10.1053/gast.2001.21193 Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 1 Mean values of individual domains of health-related quality of life in patients with cirrhosis (●) and in the normative Italian population (○, not corrected for age and gender). Note that high scores are better in the SF-36, measuring quality of life in a range from 0 to 100 (full health), whereas lower scores are better in the NHP, measuring distress in a range from 0 to 100 (full distress). Gastroenterology 2001 120, 170-178DOI: (10.1053/gast.2001.21193) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 2 Effect of age on health-related quality of life in cirrhosis. ■, Patients aged 54 years; ●, patients aged 55-64 years; and ▴, patients aged 65 years. Data are presented as means (95% CI) of Z-scores, adjusted for age and gender. All data groups whose error bars cross the zero line are not different from normative values. Note that in the SF-36 negative Z-scores denote loss of HRQL, whereas in the NHP positive Z-scores denote distress. Gastroenterology 2001 120, 170-178DOI: (10.1053/gast.2001.21193) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 3 Effect of disease severity measured by Child-Pugh class on health-related quality of life in cirrhosis. Data are presented as means (95% CI) of Z-scores, corrected for age and gender. All data groups whose error bars cross the zero line are not different from normative values. ■, Patients in Child-Pugh class A; ●, class B cases; ▴, class C cases. See also note to Figure 2. Gastroenterology 2001 120, 170-178DOI: (10.1053/gast.2001.21193) Copyright © 2001 American Gastroenterological Association Terms and Conditions

Fig. 4 Z-scores of physical and mental component summaries of SF-36 questionnaire in cirrhosis, in relation to age and Child-Pugh class. Data are presented as means and 95% CI. See also note to Figure 2. Gastroenterology 2001 120, 170-178DOI: (10.1053/gast.2001.21193) Copyright © 2001 American Gastroenterological Association Terms and Conditions