Volume 47, Issue 6, Pages (December 2017)

Slides:

Advertisements

Similar presentations

Structure of a Ubiquitin E1-E2 Complex: Insights to E1-E2 Thioester Transfer Shaun K. Olsen, Christopher D. Lima Molecular Cell Volume 49, Issue 5, Pages.

Advertisements

How T Cells Earn the Follicular Rite of Passage Carola G. Vinuesa, Jason G. Cyster Immunity Volume 35, Issue 5, Pages (November 2011) DOI: /j.immuni

Bacterial Entry to the Splenic White Pulp Initiates Antigen Presentation to CD8+ T Cells Taiki Aoshi, Bernd H. Zinselmeyer, Vjollca Konjufca, Jennifer.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2 Meghan A. Koch, Kerri R. Thomas, Nikole R.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Making Proteins in the Powerhouse B. Martin Hällberg, Nils-Göran Larsson Cell Metabolism Volume 20, Issue 2, Pages (August 2014) DOI: /j.cmet

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Plant Stomata Function in Innate Immunity against Bacterial Invasion Maeli Melotto, William Underwood, Jessica Koczan, Kinya Nomura, Sheng Yang He Cell.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

The Transcription Factor Foxo1 Controls Central-Memory CD8+ T Cell Responses to Infection Myoungjoo V. Kim, Weiming Ouyang, Will Liao, Michael Q. Zhang,

Lung Natural Helper Cells Are a Critical Source of Th2 Cell-Type Cytokines in Protease Allergen-Induced Airway Inflammation Timotheus Y.F. Halim, Ramona.

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells Julien Seneschal, Rachael A. Clark,

Evolution of the Cancer Stem Cell Model Antonija Kreso, John E. Dick Cell Stem Cell Volume 14, Issue 3, Pages (March 2014) DOI: /j.stem

IPSC Crowdsourcing: A Model for Obtaining Large Panels of Stem Cell Lines for Screening Mahendra Rao Cell Stem Cell Volume 13, Issue 4, Pages (October.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila Gerasimos P. Sykiotis, Dirk Bohmann Developmental Cell Volume 14,

A View to a Kill: The Bacterial Type VI Secretion System Brian T. Ho, Tao G. Dong, John J. Mekalanos Cell Host & Microbe Volume 15, Issue 1, Pages 9-21.

Fate Restriction and Multipotency in Retinal Stem Cells Lázaro Centanin, Burkhard Hoeckendorf, Joachim Wittbrodt Cell Stem Cell Volume 9, Issue 6, Pages.

Lung Airway-Surveilling CXCR3hi Memory CD8+ T Cells Are Critical for Protection against Influenza A Virus Bram Slütter, Lecia L. Pewe, Susan M. Kaech,

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle Isabel Beerman, Jun Seita, Matthew A.

Gastrulation Movements: the Logic and the Nuts and Bolts Maria Leptin Developmental Cell Volume 8, Issue 3, Pages (March 2005) DOI: /j.devcel

Septic Shock: On the Importance of Being Tolerant

Volume 42, Issue 2, Pages (February 2015)

Small but Mighty: Selected Commensal Bacterial Species Determine the Effectiveness of Anti-cancer Immunotherapies Jose R. Conejo-Garcia, Melanie R. Rutkowski

Sky W. Brubaker, Denise M. Monack Immunity

Joseph C. Mudd, Jason M. Brenchley Immunity

Innate DNA Sensing Moves to the Nucleus

Volume 45, Issue 1, Pages (July 2016)

The Birds, the Bees, and Innate Immunity

Volume 29, Issue 5, Pages (November 2008)

One Niche to Rule Both Maintenance and Loss of Stemness in HSCs

Dangerous Entrapment for NRF2

Chronic Infections Capture Little Attention of the Masses

Understanding Immunosuppression after Sepsis

Understanding Immunosuppression after Sepsis

POPsicle for Fever! Cooling Down the Inflammasome

CD4 Helpers Put Tissue-Resident Memory Cells in Their Place

B. Brett Finlay, Grant McFadden Cell

Volume 47, Issue 6, Pages (December 2017)

A Rogue Foxp3 Mutant Undermines Treg Cell Function

Anette H.H. van Boxel-Dezaire, M.R. Sandhya Rani, George R. Stark

Interleukin-17 Kick-Starts T Helper 1 Cell Differentiation

Chronic Infections Capture Little Attention of the Masses

E Proteins Enforce Security Checkpoints in the Thymus

A Swiss Army Knife for CTLs

Sky W. Brubaker, Denise M. Monack Immunity

ILC1 Populations Join the Border Patrol

Dangerous Liaisons: Mitochondrial DNA Meets the NLRP3 Inflammasome

Taia T. Wang, Jeffrey V. Ravetch Immunity

RAS and PD-L1: A Masters’ Liaison in Cancer Immune Evasion

Volume 143, Issue 6, (December 2010)

A Prescription for Human Immunology

Linking Inflammasome Activation and Phagosome Maturation

IL-22 from T Cells: Better Late than Never

Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome

Inflammasome: Putting the Pieces Together

MicroRNA-155 Function in B Cells

Volume 35, Issue 6, Pages (December 2011)

Volume 10, Issue 3, Pages (September 2006)

Immune Cells Exploit a Neural Circuit to Enter the CNS

Interleukin-1 Receptor 2 Keeps the Lid on Interleukin-1α

t Testing the Immune System

Volume 25, Issue 2, Pages (January 2007)

cGAS Dimerization Entangles DNA Recognition

PTENtiating CFTR for Antimicrobial Immunity

A “Big Data” View of the Tumor “Immunome”

IL-9 by INFERence Immunity

Presentation transcript:

Volume 47, Issue 6, Pages 1210-1211 (December 2017) Loss of the DNA Damage Repair Kinase ATM Impairs Inflammasome-Dependent Anti- Bacterial Innate Immunity Saskia F. Erttmann, Anetta Härtlova, Marta Sloniecka, Faizal A.M. Raffi, Ava Hosseinzadeh, Tomas Edgren, Reza Rofougaran, Ulrike Resch, Maria Fällman, Torben Ek, Nelson O. Gekara Immunity Volume 47, Issue 6, Pages 1210-1211 (December 2017) DOI: 10.1016/j.immuni.2017.11.014 Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 5 ATM Kinase Activity Is Required for the Efficient Assembly of ASC-Caspase-1 Complexes Immunity 2017 47, 1210-1211DOI: (10.1016/j.immuni.2017.11.014) Copyright © 2017 Elsevier Inc. Terms and Conditions

Figure 7 Oxidative Stress Contributes to Impaired Inflammasome Complex Assembly in Atm−/− Cells Immunity 2017 47, 1210-1211DOI: (10.1016/j.immuni.2017.11.014) Copyright © 2017 Elsevier Inc. Terms and Conditions