Stavros Stavrakis et al. JACEP 2015;1:1-13

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Stavros Stavrakis et al. JACEP 2015;1:1-13 Acute Autonomic Remodeling Induced by 6 h of Rapid Atrial Pacing in a Canine Model and Reversal by LLVNS (A) Neural activity recorded by a tungsten electrode in the anterior right ganglionated plexi (GP) increased steadily over 6 h of rapid atrial pacing. (B) Three hours (4H, 5H, and 6H) of low-level vagus nerve stimulation (LLVNS) progressively suppressed GP neural activity to baseline (BS) value (6H) despite persistence of rapid atrial pacing. (C) LLVNS for 3 h significantly reduced acetylcholine-induced atrial fibrillation (AF) duration. Stavros Stavrakis et al. JACEP 2015;1:1-13 American College of Cardiology Foundation