Volume 7, Issue 7, Pages (July 2010)

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Volume 7, Issue 7, Pages 876-882 (July 2010) Gender differences in clinical outcome and primary prevention defibrillator benefit in patients with severe left ventricular dysfunction: A systematic review and meta-analysis Pasquale Santangeli, MD, Gemma Pelargonio, MD, PhD, Antonio Dello Russo, MD, PhD, Michela Casella, MD, PhD, Caterina Bisceglia, MD, Stefano Bartoletti, MD, Pietro Santarelli, MD, Luigi Di Biase, MD, Andrea Natale, MD, FHRS Heart Rhythm Volume 7, Issue 7, Pages 876-882 (July 2010) DOI: 10.1016/j.hrthm.2010.03.042 Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 1 Selection process of studies included in the meta-analysis. Heart Rhythm 2010 7, 876-882DOI: (10.1016/j.hrthm.2010.03.042) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 2 Forest plot showing adjusted hazard ratio of overall mortality (whole study population) (A) and appropriate implantable cardioverter-defibrillator (ICD) intervention (B) in women compared to men in each study and the overall adjusted hazard ratio. Square boxes denote hazard ratio; horizontal lines represent 95% confidence interval (CI). Heart Rhythm 2010 7, 876-882DOI: (10.1016/j.hrthm.2010.03.042) Copyright © 2010 Heart Rhythm Society Terms and Conditions

Figure 3 Forest plot showing hazard ratio of survival benefit associated with implantable cardioverter-defibrillator (ICD) use in women (A) and in men (B) in each study and the overall hazard ratio. Square boxes denote hazard ratio; horizontal lines represent 95% confidence interval (CI). In SCD-HeFT, placebo denotes the no-amiodarone group; in COMPANION, placebo denotes the standard medical therapy group (no cardiac resynchronization therapy). Heart Rhythm 2010 7, 876-882DOI: (10.1016/j.hrthm.2010.03.042) Copyright © 2010 Heart Rhythm Society Terms and Conditions