Significant alterations in cysteine and methionine metabolism.

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Significant alterations in cysteine and methionine metabolism. Significant alterations in cysteine and methionine metabolism. Relative level histograms of (A) choline, SAH, and adenosine (B) MTA, SAM, and uric acid (C) NMN, NAD, and NADP. *: The significant difference, .001 < p < .05, **: .0001 < p < .001, ***: p < .0001. (D) Pearson correlation analysis of SAH and GNMT. Shancheng Ren et al. Mol Cell Proteomics 2016;15:154-163 © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.