by J. Michael Soucie, Paul E. Monahan, Roshni Kulkarni, Barbara A

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Presentation transcript:

The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B by J. Michael Soucie, Paul E. Monahan, Roshni Kulkarni, Barbara A. Konkle, and Marshall A. Mazepa BloodAdv Volume 2(16):2136-2144 August 28, 2018 ©2018 by American Society of Hematology

J. Michael Soucie et al. Blood Adv 2018;2:2136-2144 ©2018 by American Society of Hematology

Distribution of average number of joint bleeds across FA level by age groups for patients with hemophilia A. In the boxplots, the central rectangle spans the first quartile to the third quartile, a horizontal line inside the rectangle shows the median, and a circle shows the mean. Distribution of average number of joint bleeds across FA level by age groups for patients with hemophilia A. In the boxplots, the central rectangle spans the first quartile to the third quartile, a horizontal line inside the rectangle shows the median, and a circle shows the mean. Vertical lines that extend to the top of the graph indicate the presence of outlier values above 10 joint bleeds per 6-month period. J. Michael Soucie et al. Blood Adv 2018;2:2136-2144 ©2018 by American Society of Hematology

Distribution of average number of joint bleeds across factor activity level by age groups for patients with hemophilia B. In the boxplots, the central rectangle spans the first quartile to the third quartile, a horizontal line inside the rectangle shows the median, and a circle shows the mean. Distribution of average number of joint bleeds across factor activity level by age groups for patients with hemophilia B. In the boxplots, the central rectangle spans the first quartile to the third quartile, a horizontal line inside the rectangle shows the median, and a circle shows the mean. Vertical lines that extend to the top of the graph indicate the presence of outlier values above 6 joint bleeds per 6-month period. J. Michael Soucie et al. Blood Adv 2018;2:2136-2144 ©2018 by American Society of Hematology

Predicted number of joint bleeds according to factor activity level and age group for patients with hemophilia A or B based on a regression model. Predicted number of joint bleeds according to factor activity level and age group for patients with hemophilia A or B based on a regression model. Comparison of predicted number of joint bleeds per 6-month period according to FA level for a hypothetical white patient with commercial insurance, normal BMI, and HIV negativity with either hemophilia A (dashed line) or hemophilia B (solid line). J. Michael Soucie et al. Blood Adv 2018;2:2136-2144 ©2018 by American Society of Hematology