Subcategorization of Lung Cancer Based on Tumor Size and Degree of Visceral Pleural Invasion⁎ Noriaki Sakakura, MD, Shoichi Mori, MD, Katsuhiro Okuda,

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Subcategorization of Lung Cancer Based on Tumor Size and Degree of Visceral Pleural Invasion⁎ Noriaki Sakakura, MD, Shoichi Mori, MD, Katsuhiro Okuda, MD, Takayuki Fukui, MD, Shunzo Hatooka, MD, Masayuki Shinoda, MD, Keitaro Matsuo, MD, MS, Yasushi Yatabe, MD, Kohei Yokoi, MD, Tetsuya Mitsudomi, MD The Annals of Thoracic Surgery Volume 86, Issue 4, Pages 1084-1090 (October 2008) DOI: 10.1016/j.athoracsur.2008.04.117 Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Survival curves for the pathologic stages defined using the current TNM classification system. The Annals of Thoracic Surgery 2008 86, 1084-1090DOI: (10.1016/j.athoracsur.2008.04.117) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Survival curves based on tumor size. (A) The cases were divided into six groups. (B) The cases were divided into three groups. The Annals of Thoracic Surgery 2008 86, 1084-1090DOI: (10.1016/j.athoracsur.2008.04.117) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 (A) Survival curves based on the degree of pleural invasion. (B) Survival curves based on the nodal status. The Annals of Thoracic Surgery 2008 86, 1084-1090DOI: (10.1016/j.athoracsur.2008.04.117) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Analysis to stratify the pathologic T2 category into subcategories based on tumor size and the degree of visceral pleural invasion classified according to the criteria from the Japan Lung Cancer Society (P factor). The 5-year survival rates of each group are shown in the upper section of each cell. The Annals of Thoracic Surgery 2008 86, 1084-1090DOI: (10.1016/j.athoracsur.2008.04.117) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 (A) Survival curves based on our proposed pathologic T definition. (B) Survival curves based on the modified pathologic TNM staging system. The Annals of Thoracic Surgery 2008 86, 1084-1090DOI: (10.1016/j.athoracsur.2008.04.117) Copyright © 2008 The Society of Thoracic Surgeons Terms and Conditions