CD158k/KIR3DL2 Is a New Phenotypic Marker of Sezary Cells: Relevance for the Diagnosis and Follow-Up of Sezary Syndrome  Ewa Poszepczynska-Guigné, Valérie Schiavon, Michel D'Incan, Hamid Echchakir, Philippe Musette, Nicolas Ortonne, Laurence Boumsell, Alessandro Moretta, Armand Bensussan, Martine Bagot  Journal of Investigative Dermatology  Volume 122, Issue 3, Pages 820-823 (March 2004) DOI: 10.1111/j.0022-202X.2004.22326.x Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions

Figure 1 Expression of CD158k+ receptor by the malignant clonal population. (a) Double-immunofluorescence analysis of the expression of CD158k and TCRVβ2 molecules on circulating lymphocytes from a patient with 80% of Sezary cells, using fluorescein isothiocyanate (FITC) and phycoerythrin (PE). (b) CDR3 size analysis of TCRVβ2 transcripts in the CD158k+TCRVβ2+ population isolated with a flow cytometer cell sorter. (c) TCRVβ2 chain junctional region sequence of the CD158k+TCRVβ2+ sorted population. Journal of Investigative Dermatology 2004 122, 820-823DOI: (10.1111/j.0022-202X.2004.22326.x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions