Volume 53, Issue 5, Pages 1412-1416 (May 1998) Crystalluria: A clinically useful investigation in children with primary hyperoxaluria post- transplantation: Technical Note  Philippe Jouvet, Laurence Priqueler, Marie France Gagnadoux, Dominique Jan, Annick Beringer, Florence Lacaille, Yan Revillon, Michel Broyer, Michel Daudon  Kidney International  Volume 53, Issue 5, Pages 1412-1416 (May 1998) DOI: 10.1046/j.1523-1755.1998.00876.x Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 1 Diagrams of the two types of calcium oxalate crystals in urine of children with hyperoxaluria type I in the monohydrate (A) and dihydrate (B) phases. a, b, d and L are the parameters used to calculate oxalate crystal volume, and are defined in the Methods section. Kidney International 1998 53, 1412-1416DOI: (10.1046/j.1523-1755.1998.00876.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Effect of hemodialysis and frusemide on serum creatinine level, daily urine output and oxalate crystal volume evolution in a 4½-year-old girl after liver/kidney transplantation for primary hyperoxaluria type I. Symbols are: (•) creatinine serum level (μm); (□) urine output (liter/m2/24 hr), ▪ hemodialysis session, (→ frusemide administration, () oxalate crystal volume, value in brackets (μm3/mm3). Kidney International 1998 53, 1412-1416DOI: (10.1046/j.1523-1755.1998.00876.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 2 Effect of hemodialysis and frusemide on serum creatinine level, daily urine output and oxalate crystal volume evolution in a 4½-year-old girl after liver/kidney transplantation for primary hyperoxaluria type I. Symbols are: (•) creatinine serum level (μm); (□) urine output (liter/m2/24 hr), ▪ hemodialysis session, (→ frusemide administration, () oxalate crystal volume, value in brackets (μm3/mm3). Kidney International 1998 53, 1412-1416DOI: (10.1046/j.1523-1755.1998.00876.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Figure 3 Oxalate crystal volume values according to supersaturation measurements the first 10 days after combined liver/kidney transplantation in six chidren with hyperoxaluria type I. Supersaturation was calculated using the EQUIL V5 program. The dashed line is the regression line between urinary supersaturation and oxalate crystal volume [OCV = (596 × supersaturation value) -2985; P < 0.0001]. Kidney International 1998 53, 1412-1416DOI: (10.1046/j.1523-1755.1998.00876.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 53, 1412-1416DOI: (10. 1046/j. 1523-1755 Kidney International 1998 53, 1412-1416DOI: (10.1046/j.1523-1755.1998.00876.x) Copyright © 1998 International Society of Nephrology Terms and Conditions

Kidney International 1998 53, 1412-1416DOI: (10. 1046/j. 1523-1755 Kidney International 1998 53, 1412-1416DOI: (10.1046/j.1523-1755.1998.00876.x) Copyright © 1998 International Society of Nephrology Terms and Conditions