Functional interaction network based on the 234 differentially expressed genes. a) Functional network with annotated gene clusters. Functional interaction.

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Functional interaction network based on the 234 differentially expressed genes. a) Functional network with annotated gene clusters. Functional interaction network based on the 234 differentially expressed genes. a) Functional network with annotated gene clusters. Each cluster is contained within a separate NTA: grey oval, with the ID superimposed on it. b) Expression of the gene clusters in each of the mouse models. Clusters containing at least one upregulated gene are marked in pink; clusters containing at least one downregulated gene are marked in green; clusters containing both up- and downregulated genes are marked in grey. Clusters not containing any differentially expressed genes are marked by black contour. Models are sorted based on the total particulate matter used in the model: from lowest (lower left corner) to highest (upper right corner). Anna Dvorkin-Gheva et al. ERJ Open Res 2016;2:00029-2016 ©2016 by European Respiratory Society