The natural history of untreated severe or critical limb ischemia

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Presentation transcript:

The natural history of untreated severe or critical limb ischemia Abd Moain Abu Dabrh, MBBCh, MS, Mark W. Steffen, MD, MPH, Chaitanya Undavalli, MBBS, Noor Asi, MD, Zhen Wang, PhD, Mohamed B. Elamin, MD, Michael S. Conte, MD, Mohammad Hassan Murad, MD, MPH Journal of Vascular Surgery Volume 62, Issue 6, Pages 1642-1651.e3 (December 2015) DOI: 10.1016/j.jvs.2015.07.065 Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 1 Study selection process. CLI, Critical limb ischemia; RCTs, randomized controlled trials. Journal of Vascular Surgery 2015 62, 1642-1651.e3DOI: (10.1016/j.jvs.2015.07.065) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 2 Meta-analysis of mortality in patients of untreated critical limb ischemia (CLI) with follow-up ≤2 years (0) and >2 years (1) (excluding Lassila et al12). CI, Confidence interval. Journal of Vascular Surgery 2015 62, 1642-1651.e3DOI: (10.1016/j.jvs.2015.07.065) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 3 Meta-analysis of limb loss (unit of analysis = number of patients) in patients of untreated critical limb ischemia (CLI) with follow-up ≤2 years (0) and >2 years (1). CI, Confidence interval. Journal of Vascular Surgery 2015 62, 1642-1651.e3DOI: (10.1016/j.jvs.2015.07.065) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 4 Meta-analysis of limb loss (unit of analysis = number of limbs) in patients of untreated critical limb ischemia (CLI) with follow-up ≤2 years (0) and >2 years (1). CI, Confidence interval. Journal of Vascular Surgery 2015 62, 1642-1651.e3DOI: (10.1016/j.jvs.2015.07.065) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 5 Meta-analysis of ulcer or wound improvement in patients of untreated critical limb ischemia (CLI) with follow-up ≤2 years (0) and >2 years (1). CI, Confidence interval. Journal of Vascular Surgery 2015 62, 1642-1651.e3DOI: (10.1016/j.jvs.2015.07.065) Copyright © 2015 Society for Vascular Surgery Terms and Conditions

Fig 6 Meta-analysis of ulcer or wound worsening in patients of untreated critical limb ischemia (CLI) with follow-up ≤2 years (0) and >2 years (1). CI, Confidence interval. Journal of Vascular Surgery 2015 62, 1642-1651.e3DOI: (10.1016/j.jvs.2015.07.065) Copyright © 2015 Society for Vascular Surgery Terms and Conditions