Localization of a Gene for Benign Adult Familial Myoclonic Epilepsy to Chromosome 8q23.3-q24.1 Masaaki Mikami, Takeshi Yasuda, Akira Terao, Masayuki.

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Localization of a Gene for Benign Adult Familial Myoclonic Epilepsy to Chromosome 8q23.3-q24.1 Masaaki Mikami, Takeshi Yasuda, Akira Terao, Masayuki Nakamura, Shu-ichi Ueno, Hirotaka Tanabe, Toshihiro Tanaka, Teiichi Onuma, Yu-ichi Goto, Sunao Kaneko, Akira Sano The American Journal of Human Genetics Volume 65, Issue 3, Pages 745-751 (September 1999) DOI: 10.1086/302535 Copyright © 1999 The American Society of Human Genetics Terms and Conditions

Figure 1 Pedigree of a large Japanese family with BAFME. Blackened symbols indicate the affected subjects, and unblackened symbols indicate those with no signs or symptoms. A question mark (?) indicates a subject who has not been examined completely. The alleles of the 18 markers are shown under each individual, in the order indicated to the left. The American Journal of Human Genetics 1999 65, 745-751DOI: (10.1086/302535) Copyright © 1999 The American Society of Human Genetics Terms and Conditions

Figure 2 Multipoint LOD scores for genetic location on chromosome 8q. Genetic distances from D8S530 are in centimorgans. The telomere is to the right. Arrows indicate the markers that provide each LOD score. The American Journal of Human Genetics 1999 65, 745-751DOI: (10.1086/302535) Copyright © 1999 The American Society of Human Genetics Terms and Conditions

Figure 3 Genetic map of chromosome 8q region near BAFME, on the basis of the CEPH/Généthon chromosome 8 linkage map (Généthon). Relative positions of the BAFME locus and of the other three loci for epilepsy-related syndromes, familial febrile convulsions, BFNC2, and CAE are indicated. The American Journal of Human Genetics 1999 65, 745-751DOI: (10.1086/302535) Copyright © 1999 The American Society of Human Genetics Terms and Conditions