Remodeling for Demolition John C Reed, Douglas R Green  Molecular Cell  Volume 9, Issue 1, Pages 1-3 (January 2002) DOI: 10.1016/S1097-2765(02)00437-9

Figure 1 Mitochondria Remodeling during Apoptosis Two views of how mitochondria release cytochrome c. On the left (one view) is the conventional (albeit controversial) view, in which cytochrome c and other intermembrane space proteins are released either as a result of direct permeabilization of the outer membrane via a “pore” (far left), or through the opening of the permeability transition pore, matrix swelling, and rupture of the outer membrane (center). The right (another view) is that represented by the work of Scorrano et al., who suggest that there are two separable events: the permeabilization of the outer membrane via a pore and the reorganization of the cristae via a permeability transition. Molecular Cell 2002 9, 1-3DOI: (10.1016/S1097-2765(02)00437-9)